NCT00344136

Brief Summary

Heart disease and stroke disproportionately affect African Americans in the United States. These conditions are likely caused by both environmental and genetic factors. This study will attempt to identify specific genes of African and European ancestral origins that may influence the development of heart disease in African Americans.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
5,302

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Sep 2000

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2000

Completed
3.5 years until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2004

Completed
2.3 years until next milestone

First Submitted

Initial submission to the registry

June 23, 2006

Completed
3 days until next milestone

First Posted

Study publicly available on registry

June 26, 2006

Completed
Last Updated

July 29, 2016

Status Verified

October 1, 2006

First QC Date

June 23, 2006

Last Update Submit

July 28, 2016

Conditions

Heart Diseases

Keywords

Blood Pressure, HighStrokeHypertensionDiabetes MellitusObesityCerebrovascular AccidentAtherosclerosis

Eligibility Criteria

Age21 Years - 95 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Unrelated African Americans living in Hinds, Rankin, or Madison County, Mississippi enrolled in the Jackson Heart Study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Mississippi School of Medicine

Jackson, Mississippi, 39216, United States

Location

Related Publications (2)

  • Wilson JG, Rotimi CN, Ekunwe L, Royal CD, Crump ME, Wyatt SB, Steffes MW, Adeyemo A, Zhou J, Taylor HA Jr, Jaquish C. Study design for genetic analysis in the Jackson Heart Study. Ethn Dis. 2005 Autumn;15(4 Suppl 6):S6-30-37.

    PMID: 16317983BACKGROUND

  • Patterson N, Hattangadi N, Lane B, Lohmueller KE, Hafler DA, Oksenberg JR, Hauser SL, Smith MW, O'Brien SJ, Altshuler D, Daly MJ, Reich D. Methods for high-density admixture mapping of disease genes. Am J Hum Genet. 2004 May;74(5):979-1000. doi: 10.1086/420871. Epub 2004 Apr 14.

    PMID: 15088269BACKGROUND

MeSH Terms

Conditions

Heart DiseasesHypertensionStrokeDiabetes MellitusObesityAtherosclerosis

Condition Hierarchy (Ancestors)

Cardiovascular DiseasesVascular DiseasesCerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesOverweightOvernutritionNutrition DisordersBody WeightSigns and SymptomsPathological Conditions, Signs and SymptomsArteriosclerosisArterial Occlusive Diseases

Study Officials

  • James G. Wilson, MD

    University of Mississippi Medical Center and VA Medical Center, Jackson, MS

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Time Perspective
PROSPECTIVE
Sponsor Type
NIH

Study Record Dates

First Submitted

June 23, 2006

First Posted

June 26, 2006

Study Start

September 1, 2000

Study Completion

March 1, 2004

Last Updated

July 29, 2016

Record last verified: 2006-10

Locations

US(1)