NCT00337792

Brief Summary

The main objective of this study is to determine the equivalency of oral conscious sedation and intravenous conscious sedation for first trimester surgical abortion. We hypothesize that oral conscious sedation will be equivalent to intravenous conscious sedation for pain control. Additional objectives include describing subject satisfaction with each method of pain control and characteristics of each method such as side effect profile, recovery room time, and postoperative pain.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
132

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jun 2006

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2006

Completed
14 days until next milestone

First Submitted

Initial submission to the registry

June 15, 2006

Completed
1 day until next milestone

First Posted

Study publicly available on registry

June 16, 2006

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2007

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2007

Completed
Last Updated

March 18, 2016

Status Verified

March 1, 2016

Enrollment Period

1.1 years

First QC Date

June 15, 2006

Last Update Submit

March 16, 2016

Conditions

Outcome Measures

Primary Outcomes (1)

  • Pain scale

Secondary Outcomes (1)

  • Measures of satisfaction, side effects, recovery time

Interventions

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 18 or older.
  • Undesired pregnancy between 6 0/7-12 6/7 weeks gestation.
  • Has already signed consent for pregnancy termination.
  • Eligible for IV sedation per clinic protocol.

You may not qualify if:

  • Under 120 lbs.
  • Allergies to any of the drugs being studied.
  • Chronic narcotics, barbiturates or benzodiazepine use within the past year.
  • History of IV drug use within the last year.
  • Inability to give informed consent.
  • Does not speak English or Spanish and does not have translator for all study procedures
  • Previously participated in study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Planned Parenthood League of Massachusetts

Boston, Massachusetts, 02215, United States

Location

Related Publications (1)

  • Allen RH, Fitzmaurice G, Lifford KL, Lasic M, Goldberg AB. Oral compared with intravenous sedation for first-trimester surgical abortion: a randomized controlled trial. Obstet Gynecol. 2009 Feb;113(2 Pt 1):276-83. doi: 10.1097/AOG.0b013e3181938758.

MeSH Terms

Interventions

OxycodoneMidazolam

Intervention Hierarchy (Ancestors)

CodeineMorphine DerivativesMorphinansOpiate AlkaloidsAlkaloidsHeterocyclic CompoundsHeterocyclic Compounds, Bridged-RingHeterocyclic Compounds, 4 or More RingsHeterocyclic Compounds, Fused-RingPhenanthrenesPolycyclic Aromatic HydrocarbonsPolycyclic CompoundsBenzodiazepinesBenzazepinesHeterocyclic Compounds, 2-Ring

Study Officials

  • Jane Doe

    Planned Parenthood League of Massachusetts

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER

Study Record Dates

First Submitted

June 15, 2006

First Posted

June 16, 2006

Study Start

June 1, 2006

Primary Completion

July 1, 2007

Study Completion

July 1, 2007

Last Updated

March 18, 2016

Record last verified: 2016-03

Locations