NCT00336050

Brief Summary

Asthma can be caused by many factors, including mold, pollen, and other airborne pollutants. The purpose of this study is to evaluate the effect that air pollution has on the long-term severity of asthma symptoms and lung function in children.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
315

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Nov 2000

Longer than P75 for all trials

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2000

Completed
5.6 years until next milestone

First Submitted

Initial submission to the registry

June 9, 2006

Completed
3 days until next milestone

First Posted

Study publicly available on registry

June 12, 2006

Completed
4.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2010

Completed
Last Updated

July 29, 2016

Status Verified

February 1, 2009

First QC Date

June 9, 2006

Last Update Submit

July 28, 2016

Conditions

Keywords

Air PollutionPulmonary Function

Outcome Measures

Primary Outcomes (1)

  • Effect that air pollution has on the long-term severity of asthma symptoms and lung function in children

    Measured during participants' study visits

Eligibility Criteria

Age6 Years - 11 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

Convenience sample of children ages 6-11 at intake with proven asthma. All live within a radius of 20 km from the EPA Super Site in Fresno, CA

You may qualify if:

  • Asthma, as diagnosed by study criteria, which includes experiencing asthma symptoms and/or use of specific asthma medications in the 12 months prior to study entry
  • Resides within 20 kilometers of the EPA Supersite in Fresno, California
  • Is not planning to move within 3 months of study entry

You may not qualify if:

  • Current medical condition that would not allow individual to safely participate in the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Biospecimen

Retention: SAMPLES WITH DNA

Password-protected database and storage facility that is part of the UCB SPH biorepository

MeSH Terms

Conditions

Asthma

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Study Officials

  • Ira B. Tager, MD, MPH

    School of Public Health, UC Berkeley

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
NIH

Study Record Dates

First Submitted

June 9, 2006

First Posted

June 12, 2006

Study Start

November 1, 2000

Study Completion

September 1, 2010

Last Updated

July 29, 2016

Record last verified: 2009-02