NCT00325520

Brief Summary

The purpose of this study is to investigate thought processes and neural mechanisms that may contribute to the development of habitual behaviors. The investigators hypothesize that patients with AN will perform differently than people without eating disorders on a series of neuropsychological tasks and will show different neural activation patterns in functional neuroimaging scans.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
152

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started May 2006

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2006

Completed
11 days until next milestone

First Submitted

Initial submission to the registry

May 12, 2006

Completed
3 days until next milestone

First Posted

Study publicly available on registry

May 15, 2006

Completed
8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2014

Completed
Last Updated

August 15, 2014

Status Verified

July 1, 2013

Enrollment Period

8 years

First QC Date

May 12, 2006

Last Update Submit

August 14, 2014

Conditions

Anorexia Nervosa

Outcome Measures

Primary Outcomes (1)

  • Neuropsychological functioning

    pre- and post-treatment

Study Arms (2)

Anorexia nervosa

Individuals with anorexia nervosa receiving inpatient treatment

Healthy controls

Eligibility Criteria

Age16 Years - 45 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Patients with Anorexia Nervosa or Healthy Volunteers

You may qualify if:

  • DSM-IV-TR™ diagnosis of anorexia nervosa (restricting or binge-purge subtype), current or prior;
  • Age 16-45;
  • Inpatient on GCRU
  • Medically stable.

You may not qualify if:

  • Any other current major Axis I disorder (including current bulimia nervosa), except major depression;
  • History of concussion, seizure disorder, or other neurological illness;
  • History of learning disability;
  • Acute Suicidality
  • Healthy comparison group:
  • No current or past psychiatric illness;
  • Age 16-45
  • No history of binge eating or vomiting;
  • Normal weight (80%-120% ideal body weight)
  • Significant medical or neurologic illness(concussion, seizure disorder, learning disability, other neurological illness)
  • Current psychotropic medication or medications known to impact cognition
  • Significant Claustrophobia
  • Pregnancy
  • Indwelling metallic object, non-removable metal jewelry, medicinal patch or recent metallic ink tattoo
  • For patients, current psychotropic medications (antidepressants for 2 week (prozac and antipsychotics for 4 weeks)
  • +1 more criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Anorexia Nervosa

Condition Hierarchy (Ancestors)

Feeding and Eating DisordersMental Disorders

Study Officials

  • Joanna Steinglass, MD

    New York State Psychiatric Institute

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 12, 2006

First Posted

May 15, 2006

Study Start

May 1, 2006

Primary Completion

May 1, 2014

Study Completion

May 1, 2014

Last Updated

August 15, 2014

Record last verified: 2013-07