NCT00321659

Brief Summary

The overall objective of this work is to improve treatment outcomes for persons with fibromyalgia by optimizing the approach to self-management. The purpose of this research project is to evaluate and compare, in a randomized, controlled trial involving 200 women, the short and long-term effectiveness of four approaches to fibromyalgia self-management for improving health and functional status, self-efficacy, and symptom severity. Additionally, we will also examine the effect of each intervention on health care usage. We will assess the following 16-week interventions:

  • cardiovascular and flexibility exercise
  • strength training, cardiovascular and flexibility exercise
  • Arthritis Foundation's Fibromyalgia Self-Help course
  • a combination of the Fibromyalgia Self-Help Course and strength training exercise interventions

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
207

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Oct 2002

Typical duration for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 10, 2002

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 21, 2005

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 21, 2005

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

May 3, 2006

Completed
1 day until next milestone

First Posted

Study publicly available on registry

May 4, 2006

Completed
Last Updated

March 14, 2017

Status Verified

March 1, 2017

Enrollment Period

3 years

First QC Date

May 3, 2006

Last Update Submit

March 10, 2017

Conditions

Keywords

fibromyalgiaself-managementexercisepatient education

Outcome Measures

Primary Outcomes (1)

  • Fibromyalgia Impact Questionnaire

    Baseline, 16 wks and 10 months

Secondary Outcomes (7)

  • SF36 subscales

    Baseline, 16 wks and 10 months

  • Beck Depression Inventory

    Baseline, 16 wks and 10 months

  • Beck Anxiety Inventory

    Baseline, 16 wks and 10 months

  • 6 minute Walk Test

    Baseline, 16 wks and 10 months

  • 1 Repetition Maximum Chest Press

    Baseline, 16 wks and 10 months

  • +2 more secondary outcomes

Study Arms (4)

Aerobic and flexibility exercise

EXPERIMENTAL

16 weeks of aerobic and flexibility exercise. Three days per week for 1 hour of walking and cycling.

Behavioral: Aerobic

Strength, aerobic, and flexibility

EXPERIMENTAL

16 weeks of strength training, aerobic, and flexibility exercise (ST) intervention;

Behavioral: Strength training

Fibromyalgia Self-Help Course

EXPERIMENTAL

7 weeks of FSHC behavior change education

Behavioral: FSHC

a Combination of ST and FSHC

EXPERIMENTAL

16 wks of a combination of ST and FSHC (ST-FSHC) exercise and behavior change education

Behavioral: Combination

Interventions

AerobicBEHAVIORAL

3x/week of walking and cycling

Aerobic and flexibility exercise

3x/week of resistance training activities

Strength, aerobic, and flexibility
CombinationBEHAVIORAL

3x/week of aerobic and strength training activities

a Combination of ST and FSHC
FSHCBEHAVIORAL

Biweekly group education group meetings

Also known as: Fibromyalgia Self-Help Course
Fibromyalgia Self-Help Course

Eligibility Criteria

Age25 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Women aged 25 to 75 years of age
  • A confirmed diagnosis of FMS by a primary care physician (and rheumatologist if present) using the American College of Rheumatology criteria
  • Currently under care for their FMS by a primary care physician or rheumatologist
  • Determined to be medically stable by their primary care physician and capable of participation in a supervised program of low to moderate intensity exercise
  • Willingness to commit to time and travel requirements of project

You may not qualify if:

  • Do not fulfill ACR definition of FMS
  • Presence of a concurrent condition that limits a person's ability to perform the exercise program (i.e., advanced RA or OA, recent MI)
  • History of a positive exercise/stress test, or current cardiovascular, pulmonary, neurological, or renal disease where an exercise program is contraindicated
  • Uncontrolled hypertension, diabetes, asthma, or heart failure
  • Physician does not want his/her patient to participate for any reason

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (2)

  • Rooks DS, Silverman CB, Kantrowitz FG. The effects of progressive strength training and aerobic exercise on muscle strength and cardiovascular fitness in women with fibromyalgia: a pilot study. Arthritis Rheum. 2002 Feb;47(1):22-8. doi: 10.1002/art1.10180.

    PMID: 11932874BACKGROUND
  • Rooks DS, Gautam S, Romeling M, Cross ML, Stratigakis D, Evans B, Goldenberg DL, Iversen MD, Katz JN. Group exercise, education, and combination self-management in women with fibromyalgia: a randomized trial. Arch Intern Med. 2007 Nov 12;167(20):2192-200. doi: 10.1001/archinte.167.20.2192.

MeSH Terms

Conditions

FibromyalgiaMotor Activity

Interventions

Resistance Training

Condition Hierarchy (Ancestors)

Muscular DiseasesMusculoskeletal DiseasesRheumatic DiseasesNeuromuscular DiseasesNervous System DiseasesBehavior

Intervention Hierarchy (Ancestors)

Exercise TherapyRehabilitationAftercareContinuity of Patient CarePatient CareTherapeuticsPhysical Therapy ModalitiesPhysical Conditioning, HumanExerciseMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Daniel S. Rooks, PhD

    Beth Israel Deaconess Medical Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Randomized controlled trial
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

May 3, 2006

First Posted

May 4, 2006

Study Start

October 10, 2002

Primary Completion

September 21, 2005

Study Completion

September 21, 2005

Last Updated

March 14, 2017

Record last verified: 2017-03

Data Sharing

IPD Sharing
Will not share

No plan was prepared, as no data was to be shared.