Exercise Therapy and Patient Education for Individuals With Hip Osteoarthritis of the Hip. A Case-Control Study

NCT00319124 | Completed

• 1 other identifier: 03b-2005-NAR
• Study Type: observational
• Target: 52
• Locations: 1 country
• Sites: 1

Brief Summary

To identify differences between patients with OA of the hip in an early stage and a healthy control group. Hypothesis 1.1 There are significant differences between patients with OA of the hip in an early stage and a healthy control group in terms of functional capacity, biomechanical / kinematic variables, muscle strength and range of motion. Osteoarthritis (OA) is by far the most prevalent joint disorder today. The knee and the hip are large joints to be targeted and is an important cause of pain and disability. In knee OA, it is shown that significant risk factors in developing the disease are quadriceps weakness, joint instability, and changes in joint loading. A few studies on hip OA have shown altered gait pattern, which affect joint loading, and one study has shown weakness in abductors, adductors and flexors around the hip. As joint loading and muscle weakness are important factors in the development in knee OA, it might as well be factors influencing OA in the hip. The purpose of this case-control studies was to compare hip OA patients to a healthy control group regarding biomechanical and clinical differences. Patients with hip pain, activity limitations (Harris Hip Score 60-95 p) and radiographically verified hip OA was included. The healthy control group will have a Harris Hip Score of 100 p. One hundred and ten patients and fifty controls will be asked to fill in questionnaires on pain, stiffness and physical function (WOMAC), quality-of-life (SF-36 v2), self-efficacy (Lorigue), and activity (PASE) in addition to perform 6-minute walk test, sub-maximal cardiovascular function, strength, and hip range of motion tests. Additionally, Qualisys Pro reflex 3D motion analysis system will be used during walking, one-leg standing, and raising from a chair on a sub-group of 40 patients and 20 controls.

Conditions

Hip Osteoarthritis

Keywords

Hip Osteoarthritis, muscle strength, range of motion, aerobic capacity, functional capacity, health-related quality of life

Outcome Measures

Primary Outcomes (1)

• Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC)

  Baseline

Secondary Outcomes (7)

• SF-36 (quality of life)

  Baseline

• PASE (activity score)

  Baseline

• muscle strength tests (Cybex 6000)

  Baseline

• gait analysis (biomechanical analysis)

  Baseline

• 6 minutes walking test

  Baseline

Study Arms (2)

Case

Patients with hip Osteoarthritis

Control

Healthy controls without hip osteoarthritis

Eligibility Criteria

• Age: 40 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with hip osteoarthritis and mild to moderate pain. Matched controls with no hip pain.

You may qualify if:

• patients between 40 and 80 years old with uni- or bilateral hip disability
• Harris Hip Score (36) between 60 and 95.Harris Hip score(0-100 points) is widely used as an assessment of hip function in patients with hip OA. Harris Hip Score of 60 or below are used regularly at our institution as one of the criteria for hip surgery (arthroplasty).
• Patients will be included if they have more than 3 months of hip pain.
• Patients with radiographic verified hip OA (Danielson's criteria for radiographic OA: Danielsson's criteria for minimal joint space: \<4 mm \<70 years, \<3 mm ≥70 years, or 1 mm difference between hips).
• Fifty control subjects will have no health problems and no injuries or functional impairment to the lower limbs and will be matched to the patients with OA of the hip by age and gender.

You may not qualify if:

• Patients have a history of resent trauma or functional impairment to the lower limbs or diseases which might interfere with participation (rheumatoid arthritis, cancer, osteoporosis, severe back pain, knee OA).
• Patients with co-morbidities not tolerating physical activities

Sponsors & Collaborators

• Ullevaal University Hospital: lead
• Norwegian Foundation for Health and Rehabilitation: collaborator

Study Sites (1)

NAR- Department of Orthopaedics, Oslo University Hospital & Hjelp24NIMI

Oslo, Oslo County, 0407, Norway

Location

Related Publications (2)

• Rydevik K, Fernandes L, Nordsletten L, Risberg MA. Functioning and disability in patients with hip osteoarthritis with mild to moderate pain. J Orthop Sports Phys Ther. 2010 Oct;40(10):616-24. doi: 10.2519/jospt.2010.3346.

  PMID: 20811166 RESULT

• Eitzen I, Fernandes L, Nordsletten L, Risberg MA. Sagittal plane gait characteristics in hip osteoarthritis patients with mild to moderate symptoms compared to healthy controls: a cross-sectional study. BMC Musculoskelet Disord. 2012 Dec 20;13:258. doi: 10.1186/1471-2474-13-258.

  PMID: 23256709 RESULT

Related Links

• Related Info

MeSH Terms

Conditions

Osteoarthritis, Hip

Condition Hierarchy (Ancestors)

Osteoarthritis; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Study Officials

• May Arna Risberg, PT,PhD

  NAR-Department of Orthopaedics, Oslo University Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: April 27, 2006
• First Posted: April 27, 2006
• Study Start: April 1, 2005
• Primary Completion: August 1, 2008
• Study Completion: October 1, 2010
• Last Updated: March 2, 2016

Record last verified: 2012-05

Locations

NO (1)