NCT00318019

Brief Summary

In this study the food supplement OPC Factor will be tested to determine its effectiveness for increasing energy levels in healthy people aged 45-65 when compared to a placebo. All subjects will receive both active product and placebo at some time during the study. The study is nine weeks in duration. It involves three visits, taking an effervescent powder in water twice a day, and answering 24 multiple choice questions once a week. Subjects who complete the study can elect to receive a two month supply of the study product free of charge.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
27

participants targeted

Target at below P25 for phase_2 healthy

Timeline
Completed

Started Jun 2006

Typical duration for phase_2 healthy

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 21, 2006

Completed
4 days until next milestone

First Posted

Study publicly available on registry

April 25, 2006

Completed
1 month until next milestone

Study Start

First participant enrolled

June 1, 2006

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2008

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2008

Completed
Last Updated

November 17, 2011

Status Verified

November 1, 2011

Enrollment Period

1.8 years

First QC Date

April 21, 2006

Last Update Submit

November 16, 2011

Conditions

Keywords

EnergyEnergy Level

Outcome Measures

Primary Outcomes (1)

  • Energy subscore on the Activation-Deactivation Adjective Check List

    Nine weeks

Secondary Outcomes (1)

  • Four global change questions

    Nine weeks

Study Arms (2)

OPC Factor(TM)

EXPERIMENTAL
Dietary Supplement: OPC Factor(TM)

Placebo

PLACEBO COMPARATOR
Other: Placebo

Interventions

OPC Factor(TM)DIETARY_SUPPLEMENT

Evervescent poweder containing oligomeric proanthocyanidins (OPCs)and other nutrients.

OPC Factor(TM)
PlaceboOTHER

Effervescent powder similar in taste and appearance to the intervention but without the OPCs and nutrients.

Placebo

Eligibility Criteria

Age45 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • to 65 years of age at the time of recruitment

You may not qualify if:

  • Any major medical or mental illness (including a history of bipolar disorder, borderline personality disorder, and schizophrenia)
  • Medical diseases known to be associated with fatigue but not limited to:
  • AIDS
  • Anemia
  • Cancer or history of cancer (excluding basal cell carcinoma of the skin)
  • Chronic fatigue syndrome
  • Congestive heart failure
  • Chronic obstructive pulmonary disease (COPD)
  • Depression
  • Diabetes
  • Drug/alcohol dependence
  • Fibromyalgia
  • Hypertension that is uncontrolled or difficult to control
  • Hypothyroidism
  • Subjects taking the following medical therapies:
  • +12 more criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Penn Presbyterian Medical Center

Philadelphia, Pennsylvania, 19104, United States

Location

Study Officials

  • Patrick J LaRiccia, MD

    University of Pennsylvania

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 21, 2006

First Posted

April 25, 2006

Study Start

June 1, 2006

Primary Completion

April 1, 2008

Study Completion

April 1, 2008

Last Updated

November 17, 2011

Record last verified: 2011-11

Locations