Study Stopped
The study was terminated on completion of the Pilot Study phase.
Multiple Biomarkers in Undiagnosed Pleural Effusion
Evaluation of Multiple Biomarkers in Serum and Pleural Fluid to Estimate the Probability of Cancer in Patients Presenting With an Undiagnosed Pleural Effusion
1 other identifier
observational
200
1 country
1
Brief Summary
The purpose of this clinical trial is to evaluate the ability of various biomarkers measured in serum and/or pleural fluids to estimate the risk of finding cancer in patients with undiagnosed pleural effusions. An algorithm for prediction of the risk of finding cancer in the patient using an optimal combination of markers will be developed, and patients will be categorized as having a low, moderate, or high risk of finding cancer that might be used to more effectively triage patients.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Mar 2006
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2006
CompletedFirst Submitted
Initial submission to the registry
April 18, 2006
CompletedFirst Posted
Study publicly available on registry
April 20, 2006
CompletedStudy Completion
Last participant's last visit for all outcomes
February 1, 2008
CompletedNovember 8, 2011
November 1, 2011
April 18, 2006
November 7, 2011
Conditions
Keywords
Study Arms (1)
Pts scheduled to remove pleural fluid
Interventions
Diagnostic and/or therapeutic procedure to remove pleural fluid.
Eligibility Criteria
N/A - study was closed
You may qualify if:
- Subjects able to understand and sign Informed Consent;
- Males or females \>18 years of age;
- Have a pleural effusion of known or unknown origin;
- Scheduled for a diagnostic and/or therapeutic procedure to remove pleural fluid.
- Subjects able to understand and sign Informed Consent;
- Males or females \>18 years of age;
- Have a pleural effusion of unknown origin;
- Scheduled for a diagnostic procedure to remove pleural fluid.
You may not qualify if:
- For Subjects currently receiving chemotherapy and/or radiation therapy- Subjects who have received chemotherapy and/or radiation therapy must have completed these modalities one month before entering the study.
- Females known to be pregnant;
- Already entered into the study;
- Unable or unwilling to provide informed consent or is there a high risk that the subject may not comply with the protocol requirements
- For Subjects currently receiving chemotherapy and/or radiation therapy- Subjects who have received chemotherapy and/or radiation therapy must have completed these modalities one month before entering the study.
- Females known to be pregnant;
- Already entered into the study;
- Unable or unwilling to provide informed consent or is there a high risk that the subject may not comply with the protocol requirements
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Fujirebio Diagnostics, Inc
Malvern, Pennsylvania, 19355, United States
Biospecimen
Serum and pleural fluids
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Jeffrey Allard, PhD
Fujirebio Diagnostics, Inc.
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- INDUSTRY
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
April 18, 2006
First Posted
April 20, 2006
Study Start
March 1, 2006
Study Completion
February 1, 2008
Last Updated
November 8, 2011
Record last verified: 2011-11