Identifying Patients With Dementia in Primary Care

NCT00289471 | Completed Results

• 1 other identifier: IIR 05-112
• Study Type: observational
• Target: 630
• Locations: 1 country
• Sites: 1

Brief Summary

Veterans who completed GEMS-Phase 1 will be asked to participate in GEMS-Phase 2 to determine the accuracy of methods used to assess mild memory problems. This will better help us evaluate the screening test completed in GEMS-Phase 1. The goals are:

1. 1.Compare the assessment of memory made at the initial visit to assessments of memory made at the second evaluation.
2. 2.Determine of veterans with mild memory problems have improvement or worsening of these memory problems over time. Our long-term goal remains to optimize the quality of care for veterans with cognitive impairment. We will also determine if patient characteristics can be used to target case-finding, describe the current process of care and evaluate the association between cognitive impairment and overall- and dementia-related health care utilization and costs.

Conditions

Dementia; Memory Disorders

Keywords

Sensitivity and specificity; Physician's practice patterns; Health Care costs; Quality of Health Care

Outcome Measures

Primary Outcomes (1)

• Performance Characteristics

  Sensitivity and Specificity for Modified Mini-Mental Status Examination (MMSE), a measure scored 0-100 to assess cognitive impairment

  Cross-sectional [at baseline; no longitudinal component]

Study Arms (1)

Cognitive Screening

Cognitive screening

Other: No intervention delivered.

Interventions

No intervention delivered. OTHER

No intervention delivered.

Cognitive Screening

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Veterans' who have previously completed GEMS-Phase 1 testing, continues to be a VA clinic patient and identifies a key family member or friend who will answer questions about the veteran's memory and daily activities.

You may qualify if:

• Previous participant who completed GEMS-Phase 1
• Continues to be a VA clinic patient
• Identifies a key informant with phone

You may not qualify if:

• Severe hearing or visual impairment
• Acute medical condition

Sponsors & Collaborators

• US Department of Veterans Affairs: lead

Study Sites (1)

Durham VA Medical Center HSR&D COE

Durham, North Carolina, 27705, United States

Location

Related Publications (2)

• Plassman BL, Williams JW Jr, Burke JR, Holsinger T, Benjamin S. Systematic review: factors associated with risk for and possible prevention of cognitive decline in later life. Ann Intern Med. 2010 Aug 3;153(3):182-93. doi: 10.7326/0003-4819-153-3-201008030-00258. Epub 2010 Jun 14.

  PMID: 20547887 RESULT

• Holsinger T, Plassman BL, Stechuchak KM, Burke JR, Coffman CJ, Williams JW Jr. Screening for cognitive impairment: comparing the performance of four instruments in primary care. J Am Geriatr Soc. 2012 Jun;60(6):1027-36. doi: 10.1111/j.1532-5415.2012.03967.x. Epub 2012 May 30.

  PMID: 22646750 RESULT

MeSH Terms

Conditions

Dementia; Memory Disorders; Hypersensitivity

Condition Hierarchy (Ancestors)

Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Neurocognitive Disorders; Mental Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Immune System Diseases

Results Point of Contact

• Title: John W. Williams
• Organization: Durham VAMC

jw.williams@duke.edu

919-286-6963

Study Officials

• John W Williams, MD MHS

  Durham VA Medical Center

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: Yes

Study Design

• Study Type: observational
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: FED
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 8, 2006
• First Posted: February 9, 2006
• Study Start: October 1, 2009
• Primary Completion: December 1, 2009
• Study Completion: October 1, 2010
• Last Updated: May 1, 2015
• Results First Posted: August 26, 2014

Record last verified: 2015-04

Locations

US (1)