NCT00288795

Brief Summary

This research study is being conducted to compare the effectiveness of two types of complimentary medicine treatments to see if they will reduce the fatigue experienced by breast cancer patients receiving radiation therapy. The treatments being studied are Polarity Therapy and Massage Therapy. The primary study hypothesis is that Polarity Therapy will be efficacious in relieving fatigue in breast cancer patients receiving radiation treatments. The secondary hypothesis is that Polarity Therapy will be efficacious in improving health-related quality of life in breast cancer patients receiving radiation treatments.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
45

participants targeted

Target at P50-P75 for phase_1

Timeline
Completed

Started Jan 2006

Longer than P75 for phase_1

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2006

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

February 6, 2006

Completed
2 days until next milestone

First Posted

Study publicly available on registry

February 8, 2006

Completed
5.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2011

Completed
Last Updated

December 1, 2011

Status Verified

November 1, 2011

Enrollment Period

5.8 years

First QC Date

February 6, 2006

Last Update Submit

November 30, 2011

Conditions

Keywords

FatiguePolarityMassage

Outcome Measures

Primary Outcomes (1)

  • Fatigue: Brief Fatigue Inventory and the Multidimensional Fatigue Symptom Inventory; objectively via actigraphy; mood via the Fatigue/Inertia subscale of the Monopolar Profile of Mood States.

    4 wk

Secondary Outcomes (1)

  • Health -Related Quality of Life: Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F). Quality of sleep assessed subjectively with Pittsburgh Sleep Quality Inventory and a Sleep Diary.

    4 wk

Study Arms (3)

1

NO INTERVENTION

Standard Care

2

OTHER

Massage Treatment

Other: Massage Therapy

3

OTHER

Polarity Treatment

Other: Polarity Therapy

Interventions

Therapeutic Touch

2

Use of energy fields to alleviate distress and achieve balance in the body

3

Eligibility Criteria

Age21 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Diagnosis of breast cancer
  • Fatigue of 2 or greater on Symptom Inventory
  • Received at least 8 radiation treatments
  • Able to read English

You may not qualify if:

  • Be receiving concurrent chemotherapy
  • Have bone metastasizes
  • Be taking methylphenidate, modafinil, sedatives, or anxiolytics
  • Have a hemoglobin \<11g/dL.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Rochester James P. Wilmot Cancer Center

Rochester, New York, 14642, United States

Location

Related Publications (1)

  • Mustian KM, Roscoe JA, Palesh OG, Sprod LK, Heckler CE, Peppone LJ, Usuki KY, Ling MN, Brasacchio RA, Morrow GR. Polarity Therapy for cancer-related fatigue in patients with breast cancer receiving radiation therapy: a randomized controlled pilot study. Integr Cancer Ther. 2011 Mar;10(1):27-37. doi: 10.1177/1534735410397044. Epub 2011 Mar 7.

    PMID: 21382958BACKGROUND

MeSH Terms

Conditions

Fatigue

Interventions

Massage

Condition Hierarchy (Ancestors)

Signs and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Therapy, Soft TissueMusculoskeletal ManipulationsComplementary TherapiesTherapeuticsPhysical Therapy ModalitiesRehabilitation

Study Officials

  • Karen Mustian, Ph.D.

    University of Rochester

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 1
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 6, 2006

First Posted

February 8, 2006

Study Start

January 1, 2006

Primary Completion

November 1, 2011

Study Completion

November 1, 2011

Last Updated

December 1, 2011

Record last verified: 2011-11

Locations