NCT00287274

Brief Summary

Device: computerized physician order entry. We wanted to investigate if the introduction of a computerized intensive care unit system reduced the incidence and severity of medication prescription errors (MPEs). A prospective trial was conducted during 5 weeks in a paper-based unit versus a computerized unit. The registration of different classes of MPEs was done by a clinical pharmacist. An independent panel evaluated the severity of MPEs.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
160

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Mar 2004

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2004

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2004

Completed
1.8 years until next milestone

First Submitted

Initial submission to the registry

February 2, 2006

Completed
4 days until next milestone

First Posted

Study publicly available on registry

February 6, 2006

Completed
Last Updated

December 28, 2007

Status Verified

December 1, 2007

First QC Date

February 2, 2006

Last Update Submit

December 19, 2007

Conditions

Medication ErrorsPatient Safety

Outcome Measures

Primary Outcomes (1)

  • To compare the the incidence and severity of medication prescription errors between a CPOE unit and a paper-based unit at completion of the study.

Secondary Outcomes (1)

  • Description of MPEs in both units at completion of the study.

Interventions

computerized physician order entryDEVICE

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adult patients admitted to the Surgical Intensive Care Unit

You may not qualify if:

  • Adult Patients admitted to other units
  • Pediatric patients

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital Ghent

Ghent, 9000, Belgium

Location

Related Publications (1)

  • Colpaert K, Claus B, Somers A, Vandewoude K, Robays H, Decruyenaere J. Impact of computerized physician order entry on medication prescription errors in the intensive care unit: a controlled cross-sectional trial. Crit Care. 2006 Feb;10(1):R21. doi: 10.1186/cc3983.

    PMID: 16469126RESULT

Related Links

Study Officials

  • Kirsten Colpaert, MD

    University Hospital, Ghent

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER

Study Record Dates

First Submitted

February 2, 2006

First Posted

February 6, 2006

Study Start

March 1, 2004

Study Completion

April 1, 2004

Last Updated

December 28, 2007

Record last verified: 2007-12

Locations

BE(1)