NCT00287066

Brief Summary

To assess the impact of inhalation of insulin on glucose disposition in patients with type 1 diabetes

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
22

participants targeted

Target at below P25 for phase_3 diabetes-mellitus

Timeline
Completed

Started Feb 2006

Shorter than P25 for phase_3 diabetes-mellitus

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2006

Completed
1 day until next milestone

First Submitted

Initial submission to the registry

February 2, 2006

Completed
4 days until next milestone

First Posted

Study publicly available on registry

February 6, 2006

Completed
1.1 years until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2007

Completed
Last Updated

February 21, 2008

Status Verified

April 1, 2007

First QC Date

February 2, 2006

Last Update Submit

February 20, 2008

Conditions

Diabetes Mellitus

Outcome Measures

Primary Outcomes (1)

  • 18F-labeled glucose uptake in muscle

Secondary Outcomes (1)

  • Glucose turnover overnight Insulin pharmacokinetics

Interventions

Inhaled Human InsulinDRUG
Regular Human InsulinDRUG

Eligibility Criteria

Age18 Years - 50 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Diabetes mellitus Type 1

You may not qualify if:

  • Asthma, COPD
  • Smoking

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Pfizer Investigational Site

Pittsburgh, Pennsylvania, United States

Location

Related Links

MeSH Terms

Conditions

Diabetes Mellitus

Interventions

Insulin

Condition Hierarchy (Ancestors)

Glucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Intervention Hierarchy (Ancestors)

ProinsulinInsulinsPancreatic HormonesPeptide HormonesHormonesHormones, Hormone Substitutes, and Hormone AntagonistsPeptidesAmino Acids, Peptides, and Proteins

Study Officials

  • Pfizer CT.gov Call Center

    Pfizer

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
INDUSTRY

Study Record Dates

First Submitted

February 2, 2006

First Posted

February 6, 2006

Study Start

February 1, 2006

Study Completion

March 1, 2007

Last Updated

February 21, 2008

Record last verified: 2007-04

Locations

US(1)