NCT00284726

Brief Summary

The purpose of this study is to compare 2 different cold storage solutions, used to preserve donor lungs for lung transplantation, and their effect on cytokine activation related to ischemic reperfusion injury. Primary endpoint is 30 day survival.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Dec 2000

Longer than P75 for phase_3

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2000

Completed
4.8 years until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2005

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

January 31, 2006

Completed
1 day until next milestone

First Posted

Study publicly available on registry

February 1, 2006

Completed
Last Updated

September 28, 2023

Status Verified

December 1, 2017

First QC Date

January 31, 2006

Last Update Submit

September 26, 2023

Conditions

Lung Transplant Recipients

Keywords

Cytokines in lung transplantationCold storage solutionsIschemic reperfusion injury

Interventions

Celsior Cold Storage SolutionDEVICE

Eligibility Criteria

Sexall
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Any patient undergoing a lung trasnplant at Johns Hopkins Hospital -

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Officials

  • John V. Conte, M.D.

    Johns Hopkins University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 3
Sponsor Type
OTHER

Study Record Dates

First Submitted

January 31, 2006

First Posted

February 1, 2006

Study Start

December 1, 2000

Study Completion

September 1, 2005

Last Updated

September 28, 2023

Record last verified: 2017-12