NCT00282334

Brief Summary

The aim of the study is to compare telemedical antihypertensive treatment based on home blood pressure monitoring and conventional antihypertensive treatment based on monitoring of blood pressure in the doctor's office. We want to test the hypotheses that telemedical treatment is more effective in lowering blood pressure, provide better quality of life and is more cost-effective.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
236

participants targeted

Target at P50-P75 for phase_4 hypertension

Timeline
Completed

Started May 2004

Longer than P75 for phase_4 hypertension

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2004

Completed
1.7 years until next milestone

First Submitted

Initial submission to the registry

January 24, 2006

Completed
2 days until next milestone

First Posted

Study publicly available on registry

January 26, 2006

Completed
2.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2008

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2008

Completed
2.7 years until next milestone

Results Posted

Study results publicly available

July 29, 2011

Completed
Last Updated

August 1, 2011

Status Verified

July 1, 2011

Enrollment Period

4.6 years

First QC Date

January 24, 2006

Results QC Date

February 18, 2010

Last Update Submit

July 29, 2011

Conditions

Keywords

TelemedicineBlood pressureQuality of lifeCost-effectiveness

Outcome Measures

Primary Outcomes (2)

  • Difference in Number of Patients Who Reached Target Blood Pressure

    6 months

  • Difference in Mean Daytime Systolic Ambulatory Blood Pressure From Baseline to Follow-up After Six Months

    Comparison of mean change in daytime systolic ambulatory blood pressure from baseline to follow up after 6 months between the two groups

    baseline and 6 months

Study Arms (2)

Home blood pressure telemonitoring

EXPERIMENTAL
Device: Telemedical blood pressure monitoring

Conventional blood pressure monitoring

NO INTERVENTION

Interventions

Measurement of home blood pressure, three times per week for three months and once a week for three months.

Home blood pressure telemonitoring

Eligibility Criteria

Age20 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • age 20 - 80 years
  • office blood pressure \> 150/95 mmHg or systolic blood pressure \>150 mmHg and diastolic blood pressure \< 90 mmHg

You may not qualify if:

  • not able to perform home blood pressure measurements
  • low compliance
  • abuse of alcohol/ medicine
  • unwillingness to participate

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Dept. of Medical Research, Holstebro Hospital

Holstebro, 7500, Denmark

Location

Related Publications (1)

  • Madsen LB, Christiansen T, Kirkegaard P, Pedersen EB. Economic evaluation of home blood pressure telemonitoring: a randomized controlled trial. Blood Press. 2011 Apr;20(2):117-25. doi: 10.3109/08037051.2010.532306. Epub 2010 Nov 24.

MeSH Terms

Conditions

Hypertension

Condition Hierarchy (Ancestors)

Vascular DiseasesCardiovascular Diseases

Limitations and Caveats

Technical difficulties with telemedical equipment,referral bias,unblinded study

Results Point of Contact

Title
Line Bille Madsen
Organization
Dept. of Medical Research, Holstebro Hospital

Study Officials

  • Line B Madsen, MD

    Dept. of Medical Research, Holstebro Hospital, 7500 Holstebro, Denmark

    PRINCIPAL INVESTIGATOR
  • Erling B Pedersen, Professor

    Dept. of Medical Research, Holstebro Hospital, 7500 Holstebro, Denmark

    STUDY CHAIR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

January 24, 2006

First Posted

January 26, 2006

Study Start

May 1, 2004

Primary Completion

December 1, 2008

Study Completion

December 1, 2008

Last Updated

August 1, 2011

Results First Posted

July 29, 2011

Record last verified: 2011-07

Locations