CBT for Comorbid Anxiety Disorders in Children With Autism, Asperger Syndrome, or PDD-NOS
BIACA
1 other identifier
interventional
20
1 country
1
Brief Summary
This study is designed to examine the efficacy of a cognitive behavioral therapy (CBT) program for treating anxiety symptoms, social problems, and adaptive behavior deficits in children with autism spectrum disorders.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for phase_2
Started Jan 2005
Typical duration for phase_2
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2005
CompletedFirst Submitted
Initial submission to the registry
January 20, 2006
CompletedFirst Posted
Study publicly available on registry
January 23, 2006
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2008
CompletedStudy Completion
Last participant's last visit for all outcomes
August 1, 2009
CompletedApril 2, 2012
March 1, 2012
3.6 years
January 20, 2006
March 28, 2012
Conditions
Outcome Measures
Primary Outcomes (2)
Score on anxiety diagnostic interview after treatment or waitlist
post-treatment
Score on anxiety rating scale after treatment or waitlist
post-treatment
Secondary Outcomes (2)
Score on daily living skills rating scale after treatment or waitlist
post-treatment
Score on children's social functioning and service use after treatment or waitlist
post-treatment
Study Arms (2)
Cognitive Behavioral Therapy
EXPERIMENTALWaitlist
NO INTERVENTIONInterventions
Cognitive behavioral therapy for children with autism and anxiety.
Eligibility Criteria
You may qualify if:
- years of age
- Meet research criteria for a diagnosis of Asperger Syndrome or PDD-NOS
- Meet DSM-IV criteria for one of the following anxiety disorders: Separation Anxiety Disorder, Social Phobia, Obsessive-Compulsive Disorder
- If taking medication, have maintained a stable dose for 1 month prior to baseline assessment
You may not qualify if:
- Child has an IQ of less than 70
- Begin taking new medication(s) or current medication dose changes either (1) less than 1 month prior to baseline assessment, or (2) during the study period
- For any reason the child or parents appear unable to participate in the treatment program
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of California, Los Angeles
Los Angeles, California, 90095, United States
Related Publications (1)
Wood JJ, Drahota A, Sze K, Har K, Chiu A, Langer DA. Cognitive behavioral therapy for anxiety in children with autism spectrum disorders: a randomized, controlled trial. J Child Psychol Psychiatry. 2009 Mar;50(3):224-34. doi: 10.1111/j.1469-7610.2008.01948.x.
PMID: 19309326DERIVED
Related Links
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Jeffrey J Wood, Ph.D.
University of California, Los Angeles
Study Design
- Study Type
- interventional
- Phase
- phase 2
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
January 20, 2006
First Posted
January 23, 2006
Study Start
January 1, 2005
Primary Completion
August 1, 2008
Study Completion
August 1, 2009
Last Updated
April 2, 2012
Record last verified: 2012-03