Comparison of Femoral Versus Jugular Routes for Temporary Hemodialysis in Seriously Ill Patients
CATHEDIA
Complications of Jugular and Femoral Venous Catheterization in Critically Ill Patients Requiring Hemodialysis: A Randomized Controlled Trial
1 other identifier
interventional
750
1 country
10
Brief Summary
The purpose of this study is to determine whether a jugular route leads to a lower rate of complications as compared with a femoral route for catheterization in patients admitted in several intensive care units in France who develop acute renal failure requiring hemodiafiltration or hemodialysis.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Apr 2004
Typical duration for not_applicable
10 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 1, 2004
CompletedFirst Submitted
Initial submission to the registry
January 13, 2006
CompletedFirst Posted
Study publicly available on registry
January 18, 2006
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 1, 2007
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2007
CompletedNovember 14, 2014
November 1, 2014
3.1 years
January 13, 2006
November 13, 2014
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Time of insertion without complication
Secondary Outcomes (3)
Rates of mechanical complications
Rates of infectious complications including cath-colonization
Quality of hemodialysis by urea extraction ratio
Study Arms (2)
Femoral route
EXPERIMENTALJugular route
EXPERIMENTALInterventions
Eligibility Criteria
You may qualify if:
- Admitted in intensive care unit (ICU)
- Requiring hemodialysis
- Clinicians have the choice between jugular and femoral routes
You may not qualify if:
- Chronic renal failure requiring long term dialysis
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (10)
Medical and nephrologic Intensive Care Unit, CHU Amien Sud
Amiens, 80000, France
CH Argenteuil
Argenteuil, 95100, France
Medical Intensive Care Unit, CHU de Caen
Caen, 14000, France
Surgical Intensive Care Unit
Caen, 14033, France
CHU de Clermont Ferrand
Clermont-Ferrand, France
CHU Raymond Pointcarré
Garches, 92380, France
Hôpital Cochin
Paris, 75679, France
Hôpital Lariboisière
Paris, 75, France
Hôpital St Joseph
Paris, 75, France
CH Saint Malo
St-Malo, France
Related Publications (7)
Parienti JJ, Thirion M, Megarbane B, Souweine B, Ouchikhe A, Polito A, Forel JM, Marque S, Misset B, Airapetian N, Daurel C, Mira JP, Ramakers M, du Cheyron D, Le Coutour X, Daubin C, Charbonneau P; Members of the Cathedia Study Group. Femoral vs jugular venous catheterization and risk of nosocomial events in adults requiring acute renal replacement therapy: a randomized controlled trial. JAMA. 2008 May 28;299(20):2413-22. doi: 10.1001/jama.299.20.2413.
PMID: 18505951RESULTParienti JJ, Megarbane B, Fischer MO, Lautrette A, Gazui N, Marin N, Hanouz JL, Ramakers M, Daubin C, Mira JP, Charbonneau P, du Cheyron D; Cathedia Study Group. Catheter dysfunction and dialysis performance according to vascular access among 736 critically ill adults requiring renal replacement therapy: a randomized controlled study. Crit Care Med. 2010 Apr;38(4):1118-25. doi: 10.1097/CCM.0b013e3181d454b3.
PMID: 20154599RESULTParienti JJ, Dugue AE, Daurel C, Mira JP, Megarbane B, Mermel LA, Daubin C, du Cheyron D; Members of the Cathedia Study Group. Continuous renal replacement therapy may increase the risk of catheter infection. Clin J Am Soc Nephrol. 2010 Aug;5(8):1489-96. doi: 10.2215/CJN.02130310. Epub 2010 Jun 17.
PMID: 20558562RESULTDugue AE, Levesque SP, Fischer MO, Souweine B, Mira JP, Megarbane B, Daubin C, du Cheyron D, Parienti JJ; Cathedia Study Group. Vascular access sites for acute renal replacement in intensive care units. Clin J Am Soc Nephrol. 2012 Jan;7(1):70-7. doi: 10.2215/CJN.06570711. Epub 2011 Nov 10.
PMID: 22076877RESULTParienti JJ, Deryckere S, Megarbane B, Valette X, Seguin A, Sauneuf B, Mira JP, Souweine B, Cattoir V, Daubin C, du Cheyron D; Cathedia Study Group. Quasi-experimental study of sodium citrate locks and the risk of acute hemodialysis catheter infection among critically ill patients. Antimicrob Agents Chemother. 2014 Oct;58(10):5666-72. doi: 10.1128/AAC.03079-14. Epub 2014 Jun 30.
PMID: 24982071RESULTIachkine J, Buetti N, de Grooth HJ, Briant AR, Mimoz O, Megarbane B, Mira JP, Ruckly S, Souweine B, du Cheyron D, Mermel LA, Timsit JF, Parienti JJ. Development and validation of a multivariable prediction model of central venous catheter-tip colonization in a cohort of five randomized trials. Crit Care. 2022 Jul 7;26(1):205. doi: 10.1186/s13054-022-04078-x.
PMID: 35799302DERIVEDTsujimoto Y, Miki S, Shimada H, Tsujimoto H, Yasuda H, Kataoka Y, Fujii T. Non-pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement therapy. Cochrane Database Syst Rev. 2021 Sep 14;9(9):CD013330. doi: 10.1002/14651858.CD013330.pub2.
PMID: 34519356DERIVED
Related Links
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Jean-Jacques Parienti, MD
University Hospital, Caen
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
January 13, 2006
First Posted
January 18, 2006
Study Start
April 1, 2004
Primary Completion
May 1, 2007
Study Completion
May 1, 2007
Last Updated
November 14, 2014
Record last verified: 2014-11