NCT00269139

Brief Summary

Dr. Laddis will test a hypothesis about the nature and the management of behavioral crises in patients with borderline personality disorder (BPD) or post-traumatic stress disorder (PTSD). The term "behavioral crisis" is used strictly for periods of uncontrollable urges to repeat mental or outward activity, e.g., flashbacks, cutting, binging on food, drugs or sex, with no intervals to rethink one's priorities or to consider others' direction. The clinical hypothesis states, in two steps, that:

  1. 1.the perception of a life crisis precedes and then underlies every behavioral crisis;
  2. 2.the behavioral crisis resolves promptly and all symptoms end if the clinicians engage the patient about his management of the life crisis that underlies the symptoms.

Trial Health

55
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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P50-P75 for phase_1

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 21, 2005

Completed
2 days until next milestone

First Posted

Study publicly available on registry

December 23, 2005

Completed
Last Updated

February 20, 2006

Status Verified

December 1, 2005

First QC Date

December 21, 2005

Last Update Submit

February 17, 2006

Conditions

Borderline Personality DisorderPost-Traumatic Stress Disorders

Keywords

Behavioral crisisPerception of social crisisRepetition compulsionIntrusive mental eventsUncontrollable urges

Outcome Measures

Primary Outcomes (2)

  • Brief Psychiatric Rating Scale (BPRS) scores

  • Scores on Client Observation and Client Interview, tools designed for this study

Secondary Outcomes (2)

  • Patient interview and ratings for the value of the clinicians' interventions

  • Staff interview and ratings for their own interventions

Interventions

Crisis resolutionBEHAVIORAL

Eligibility Criteria

Age19 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Diagnosed with BPD or PTSD, with a structured interview according to the current diagnostic manual
  • In behavioral crisis

You may not qualify if:

  • Brain damage
  • Currently intoxicated with alcohol or drugs or in withdrawal

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cape Cod and Islands Community Mental Health Center

Pocasset, Massachusetts, 02559, United States

Location

Related Publications (1)

  • Laddis A. Outcome of crisis intervention for borderline personality disorder and post traumatic stress disorder: a model for modification of the mechanism of disorder in complex post traumatic syndromes. Ann Gen Psychiatry. 2010 Apr 27;9:19. doi: 10.1186/1744-859X-9-19.

    PMID: 20420716DERIVED

MeSH Terms

Conditions

Borderline Personality DisorderStress Disorders, Post-Traumatic

Condition Hierarchy (Ancestors)

Personality DisordersMental DisordersStress Disorders, TraumaticTrauma and Stressor Related Disorders

Study Officials

  • Andreas Laddis, MD

    Cape Cod and Islands Community Mental Health Center

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Andreas Laddis, MD

CONTACT

508-320-7895andreas.laddis@dmh.state.ma.us

Study Design

Study Type
interventional
Phase
phase 1
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDIV

Study Record Dates

First Submitted

December 21, 2005

First Posted

December 23, 2005

Last Updated

February 20, 2006

Record last verified: 2005-12

Locations

US(1)