NCT00266383

Brief Summary

The human homologue of mice natural-resistance-associated macrophage protein 1 (Nramp 1) gene, NRAMP 1, has been reported to play a role in the susceptibility to tuberculosis in humans. The aboriginal population in Taiwan has a 5-fold higher prevalence of tuberculosis than the Han Chinese. Whether genetic factors such as NRAMP 1 polymorphisms play a role in the prevalence of tuberculosis in Taiwanese aboriginals should be clarified.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
250

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2005

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2005

Completed
11 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2005

Completed
14 days until next milestone

First Submitted

Initial submission to the registry

December 15, 2005

Completed
1 day until next milestone

First Posted

Study publicly available on registry

December 16, 2005

Completed
Last Updated

December 19, 2005

Status Verified

December 1, 2005

First QC Date

December 15, 2005

Last Update Submit

December 16, 2005

Conditions

Tuberculosis

Eligibility Criteria

Age0 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • The NRAMP 1 polymorphism of tuberculous patients in Taiwan.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

National Health Research Institutes

Miaoli County, Taiwan

Location

MeSH Terms

Conditions

Tuberculosis

Condition Hierarchy (Ancestors)

Mycobacterium InfectionsActinomycetales InfectionsGram-Positive Bacterial InfectionsBacterial InfectionsBacterial Infections and MycosesInfections

Study Officials

  • Ih-Jen Su, M.D., Ph.D.

    Division of Clinical Research, National Health Research Institutes

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
OTHER
Sponsor Type
OTHER

Study Record Dates

First Submitted

December 15, 2005

First Posted

December 16, 2005

Study Start

January 1, 2005

Study Completion

December 1, 2005

Last Updated

December 19, 2005

Record last verified: 2005-12

Locations

TW(1)