NCT00263380

Brief Summary

Research on the synergistic effect of corticosteroids and beta-agonists on the cytokine production in COPD patients. Blood will be obtained from healthy volunteers and COPD patients and blood monocytes will be stimulated to produce cytokines with or without the prementioned drugs.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
90

participants targeted

Target at P50-P75 for all trials

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2005

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

December 7, 2005

Completed
1 day until next milestone

First Posted

Study publicly available on registry

December 8, 2005

Completed
Last Updated

September 11, 2006

Status Verified

July 1, 2005

First QC Date

December 7, 2005

Last Update Submit

September 8, 2006

Conditions

COPD

Keywords

COPDcytokinescorticosteroidsbeta agonistssynergistic effect

Eligibility Criteria

Age40 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • clinical COPD
  • smoking
  • age \> 40 years

You may not qualify if:

  • age \< 40 years
  • use of antibiotics, corticosteroids or beta-agonists

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

St Antonius Hospital

Nieuwegein, Utrecht, 3435 CM, Netherlands

RECRUITING

St Antonius Hospital

Nieuwegein, Utrecht, 3435 CM, Netherlands

RECRUITING

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, ObstructiveLung DiseasesRespiratory Tract DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Robert Ten Broeke, Dr

    St. Antonius Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

December 7, 2005

First Posted

December 8, 2005

Study Start

October 1, 2005

Last Updated

September 11, 2006

Record last verified: 2005-07

Locations

NL(2)