NCT00256464

Brief Summary

The principal aim of this project is to conduct a Randomized Controlled Trial (RCT) to examine whether adding a twelve-session Multi-Component Yoga Intervention (MCYI) to the treatment regimen of Australian Vietnam Veterans suffering chronic Posttraumatic Stress Disorder (PTSD) leads to a significantly greater clinical improvement than conventional psychiatric treatment alone. Include 12 sessions with each session 3 hours duration- 4 days per week for 3 weeks i.e. total of 36 hours. The Multi-Component Yoga Intervention (MCYI) consisting of specific poses, breathing techniques, information about yoga techniques and practices, group processes, psychoeducation, relaxation procedures and meditation techniques in Vietnam War Veterans with chronic Posttraumatic Stress Disorder (PTSD) resistant to treatment has been developed. This project aims to evaluate MCYI through RCT method. It is hypothesised that Yoga augmentation will lead to: (1) reduced symptoms of PTSD and Depression; and (2) reduced alcohol intake. A secondary aim of the proposed RCT is to evaluate putative mediating variables. Benefits include that it is low cost and easy to apply. Done at home, non threatening and additional to standard psychiatric treatment for PTSD.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at P25-P50 for phase_1

Timeline
Completed

Started Jun 2007

Shorter than P25 for phase_1

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 16, 2005

Completed
5 days until next milestone

First Posted

Study publicly available on registry

November 21, 2005

Completed
1.5 years until next milestone

Study Start

First participant enrolled

June 1, 2007

Completed
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2008

Completed
Last Updated

September 8, 2006

Status Verified

August 1, 2005

First QC Date

November 16, 2005

Last Update Submit

September 7, 2006

Conditions

Keywords

PTSD

Outcome Measures

Primary Outcomes (2)

  • Decreased symptoms of posttraumatic stress disorder

  • Decreased symptoms of comorbid conditions of depression and alcohol dependence

Interventions

Eligibility Criteria

Age50 Years - 70 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Symptoms of PTSD DSM IV for a minimum of 12 months prior to screening meeting Mini Plus
  • Satisfy CAPS test for PTSD having all criterions
  • Alcohol Audit with a score of 8 or less in dependence
  • An absence of suicidal intent, organic brain disease, absence of present psychosis identified

You may not qualify if:

  • History of psychosis
  • Subject with greater than 20% reduction in their CAPS 2 score between screening and baseline
  • Those who are acutely suicidal
  • Current substance dependence or abuse exept for alcohol
  • Subject requiring electro convulsive therapy or who have had recent ECT which may cause interference with cognitive function.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Links

MeSH Terms

Conditions

Stress Disorders, Post-TraumaticDepression

Condition Hierarchy (Ancestors)

Stress Disorders, TraumaticTrauma and Stressor Related DisordersMental DisordersBehavioral SymptomsBehavior

Study Officials

  • Janis J Carter, MBBS FRANZCP

    The University of Queensland

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Janis J Carter, MBBS FRANZCP

CONTACT

Study Design

Study Type
interventional
Phase
phase 1
Allocation
RANDOMIZED
Masking
SINGLE
Purpose
ECT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER

Study Record Dates

First Submitted

November 16, 2005

First Posted

November 21, 2005

Study Start

June 1, 2007

Study Completion

January 1, 2008

Last Updated

September 8, 2006

Record last verified: 2005-08