Pre-Clinical Models in Gynecological Tumors A Tissue Repository

NCT00250783 | Completed DMC

• 1 other identifier: 2902C
• Study Type: observational
• Target: 26
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to provide a repository for long-term storage of endometrial cancer tumor and normal tissue, ascites and serum. This material will be used in studies to better understand the molecular biology of endometrial cancer.

Conditions

Endometrial Neoplasms; Uterine Neoplasms

Keywords

Corpus Uteri; Endometrium; Cancer

Eligibility Criteria

• Age: 18 Years+
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

tumor and normal tissues, ascites, and/or serum, and/or urine from women with malignant or premalignant gynecological conditions for which they are undergoing medically-indicated surgery, and normal tissues from women without malignancy who volunteer to donate serum and/or tissue at the time of medically indicated surgery.

You may qualify if:

• All patients undergoing hysterectomy, or who have endometrial cancer, and are under routine surveillance.
• Patients may have received prior hormonal, cytotoxic chemotherapy, irradiation or surgical therapy.
• Healthy post-menopausal and peri-menopausal women.
• A consent form must be signed by the patient prior to study entry.

You may not qualify if:

• Study Patients:
• Patients who do not have primary uterine corpus tumors.
• Patients with less than one gram of tumor tissue available to procurement.
• Controls:
• Patients unwilling to have their medical records reviewed for height, weight, and general medical history (see attached data sheets).

Sponsors & Collaborators

• University of New Mexico: lead

Study Sites (1)

University of New Mexico

Albuquerque, New Mexico, 87131, United States

Location

Biospecimen

Retention: SAMPLES WITHOUT DNA

Tumor and normal tissues, ascites, and/or serum, and/or urine from women with malignant or premalignant gynecological conditions for which they are undergoing medically-indicated surgery, and normal tissues from women without malignancy who volunteer to donate serum and/or tissue at the time of medically indicated surgery

MeSH Terms

Conditions

Endometrial Neoplasms; Uterine Neoplasms; Neoplasms

Condition Hierarchy (Ancestors)

Genital Neoplasms, Female; Urogenital Neoplasms; Neoplasms by Site; Uterine Diseases; Genital Diseases, Female; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Genital Diseases

Study Officials

• Harriet Smith, MD

  University of New Mexico

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 4, 2005
• First Posted: November 8, 2005
• Study Start: July 1, 2002
• Primary Completion: January 1, 2008
• Study Completion: January 1, 2008
• Last Updated: March 12, 2024

Record last verified: 2024-03

Locations

US (1)