NCT00248729

Brief Summary

The objective of this study was to compare the utility of etomidate and midazolam in helping patients to relax when there was a need for the placement of a ventilation tube by medics who were transporting patients to a hospital in an ambulance.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Oct 2002

Typical duration for phase_2

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2002

Completed
3.1 years until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2005

Completed
1 day until next milestone

First Submitted

Initial submission to the registry

November 2, 2005

Completed
2 days until next milestone

First Posted

Study publicly available on registry

November 4, 2005

Completed
Last Updated

May 14, 2025

Status Verified

May 1, 2025

First QC Date

November 2, 2005

Last Update Submit

May 13, 2025

Conditions

Respiratory Failure

Interventions

Etomidate (20mg) or Midazolam (7mg)DRUG

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Under the study protocol, all patients age 18 or over transported by the two participating ALS systems, requiring pre-hospital Sedation Facilitated Intubation, were eligible for participation.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

St. Luke's Hospital

Bethlehem, Pennsylvania, 18015, United States

Location

MeSH Terms

Conditions

Respiratory Insufficiency

Interventions

EtomidateMidazolam

Condition Hierarchy (Ancestors)

Respiration DisordersRespiratory Tract Diseases

Intervention Hierarchy (Ancestors)

ImidazolesAzolesHeterocyclic Compounds, 1-RingHeterocyclic CompoundsBenzodiazepinesBenzazepinesHeterocyclic Compounds, 2-RingHeterocyclic Compounds, Fused-Ring

Study Officials

  • Jeanne L Jacoby, MD

    St. Luke's Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
DOUBLE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER

Study Record Dates

First Submitted

November 2, 2005

First Posted

November 4, 2005

Study Start

October 1, 2002

Study Completion

November 1, 2005

Last Updated

May 14, 2025

Record last verified: 2025-05

Locations

US(1)