Motivationally-Enhanced Brief Interpersonal Psychotherapy for Depressed Mothers of Ill Children

NCT00245193 | Completed Phase 4

• 2 other identifiers: K23MH064518DSIR 8K-RTAT
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

This study will investigate the effectiveness of motivationally-enhanced brief interpersonal psychotherapy (MI-IPT-B) in treating depression in mothers who bring their children to a child mental health clinic for psychiatric treatment.

Conditions

Depression

Keywords

Major Depression

Outcome Measures

Primary Outcomes (1)

• Score on the Hamilton Rating Scale for Depression; measured at baseline, Week 14, and Month 6

Secondary Outcomes (1)

• Score on the Beck Depression Inventory; measured at baseline, Week 14, and Month 6

Interventions

Motivationally-Enhanced Interpersonal Psychotherapy BEHAVIORAL

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Biological or adoptive mother whose child between the ages of 6 and 18 is treated in the Services for Teens at Risk (STAR) Center or the Center for Children and Families (CCF)
• Mother lives with and has custody of the child receiving treatment
• Meets DSM-IV criteria for current unipolar depressive disorder (e.g., dysthymic disorder, depressive disorder, or single or recurrent episodes of major depressive disorder)
• Score of greater than 16 on the Beck Depression Inventory
• Score of greater than 15 on the Hamilton Rating Scale for Depression (17-item)
• Willingness to maintain existing stable dose of antidepressant medication throughout the study if currently on medication and still experiencing symptoms of depression
• Willingness of child (treated in STAR clinic or CCF) to give informed consent

You may not qualify if:

• Currently receiving antidepressant medication at sub-therapeutic doses or at therapeutic doses but for an inadequate period of time to assess response
• Current dose of medication has not been stable for at least 8 weeks prior to study enrollment
• Suicidal or homicidal
• Requires hospitalization
• At risk for child abuse or neglect and requires intervention
• Simultaneous psychotic disorder or organic mental disorder
• History of drug or alcohol abuse within 6 months of study enrollment
• History of a prior manic episode
• Significant medical illness that might explain depressive symptoms (e.g., epilepsy, autoimmune disorders, liver dysfunction, unstable endocrine disease)
• Not fluent in English
• Severe cognitive deficits that would interfere with psychotherapy treatment
• Currently receiving another form of individual psychotherapy or couples therapy (except for participation in a support group, such as Alcoholics Anonymous)

Sponsors & Collaborators

• University of Pittsburgh: lead

Study Sites (1)

Western Psychiatric Institute and Clinic

Pittsburgh, Pennsylvania, 15231, United States

Location

MeSH Terms

Conditions

Depression; Depressive Disorder, Major

Condition Hierarchy (Ancestors)

Behavioral Symptoms; Behavior; Depressive Disorder; Mood Disorders; Mental Disorders

Study Officials

• Holly Swartz, MD

  University of Pittsburgh

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: phase 4
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: October 25, 2005
• First Posted: October 27, 2005
• Study Start: April 1, 2003
• Study Completion: March 1, 2006
• Last Updated: June 25, 2013

Record last verified: 2013-06

Locations

US (1)