Too much difficulty recruiting and retaining patients, PI decided to stop.
A Randomized Study to Compare the Acne Relapse Rate After a 3-mo Course of Oral Minocycline, to a 3-mo Course of Oral Minocycline in Combination With a Daily Dose of Topical Tretinoin 0.01% Followed by 3 mo of Topical Tretinoin Alone
Sponsor study identifier
interventional
38
1 country
1
Study Start
August 2004
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
December 2006
Actual (reported)Study Completion
December 2006
Actual (reported)The use of oral antibiotics alone to treat inflammatory acne provides little to no long term therapeutic benefit. Acne relapse rates can be reduced by using topical tretinoin 0.01% in conjunction with minocycline, thereby increasing the therapeutic effect of the oral antibiotic.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 2006
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
August 2004
Date type not reportedThis date has not been verified as actual or estimated.
October 16, 2005
Actual (reported)October 18, 2005
Actual (reported)December 2006
Actual (reported)December 2006
Actual (reported)Long-term efficacy
4 years
Relapse rate
4 years
Minocycline 3 mo
Minocycline plus Tretinoin for 3 months
100 mg capsules OD for 3 months
100mg OD Minocycline for 12 weeks plus OD Topical tretinoin 0.01% for 12 weeks Followed by topical tretinoin 0.01% OD for 12 weeks alone
These entries preserve how the registry describes the intervention. Their treatment roles are shown separately from molecular identities.
Grouped treatment entry
Minocycline plus tretinoin
The registry names several treatments. This does not confirm that participants received them together or that they form a single product.
View registry recordDerm Research @ 888 Inc
Vancouver, British Columbia, V5Z 3Y1, Canada
Richard Thomas, MD, FRCP(C)
DermResearch @ 888 Inc.
38 participants (actual enrollment reported by the registry).
First Submitted
October 16, 2005
First Posted
October 18, 2005
Study Start
August 2004
Date type not reportedThis date has not been verified as actual or estimated.
Measuring Adherence in Subjects With Acne Vulgaris in a Clinic Population Subtitle: Topical Benzoyl Peroxide for Acne
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
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Primary Completion
December 2006
Actual (reported)Study Completion
December 2006
Actual (reported)Last Updated
February 24, 2012
Record last verified: 2012-02
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Source: ClinicalTrials.gov.
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