NCT00238888

Brief Summary

The objectives of this trials are to demonstrate, in children with poorly controlled asthma, that an intervention to increase the awareness and the impact of poor asthma control among parents and physicians of affected children and adolescents can reduce the rate of asthma emergency visits in the 12 months following the initiation of the intervention.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
298

participants targeted

Target at P75+ for phase_4 asthma

Timeline
Completed

Started Aug 2002

Longer than P75 for phase_4 asthma

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2002

Completed
3.2 years until next milestone

First Submitted

Initial submission to the registry

October 12, 2005

Completed
2 days until next milestone

First Posted

Study publicly available on registry

October 14, 2005

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2007

Completed
4.7 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2011

Completed
Last Updated

April 20, 2017

Status Verified

April 1, 2017

Enrollment Period

4.7 years

First QC Date

October 12, 2005

Last Update Submit

April 18, 2017

Conditions

Keywords

asthmachildrenadolescenteducationmedical reviewasthma controlquestionnairequality of lifeemergency department visituse of medicationadherence to treatment

Outcome Measures

Primary Outcomes (1)

  • rate of emergency department (ED) visits per person-month of observation, derived from Quebec provincial database (RAMQ) data.

    rate of ED visit derived from provincial administrative databases

    1 year

Secondary Outcomes (4)

  • Usage of asthma medication (refill rate of reliever drugs, ratio of reliever/preventer drugs; rate of rescue systemic steroids) as assessed from pharmacy records and RAMQ data

    1 year after randomisation

  • Quality of life of the child and caregivers using Juniper's instruments

    1 year after randomisation

  • Change in asthma control between baseline and 12 months

    1 year after randomisation

  • Health care resources utilisation for asthma care (hospitalisation for asthma, hospitalisation for any cause, ratio of clinic to emergency department, as reflection of the ratio of preventive over curative care).

    1 year after randomisation

Study Arms (2)

Asthma control awareness

EXPERIMENTAL

Multifaceted intervention to increase the patient awareness of the leve of asthma control

Procedure: asthma control awareness

Usual care

ACTIVE COMPARATOR

Usual care

Procedure: Usual care

Interventions

Repeated assessments of the child's asthma control using the Asthma Quiz for Kidz, with recommendation for asthma education and medical visit

Asthma control awareness
Usual carePROCEDURE

Recommendation for asthma education and/or follow-up at the physician's discretion

Usual care

Eligibility Criteria

Age5 Years - 17 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Children between 6 and 17 years of
  • acute asthma requiring emergency room visit or hospital admission
  • understanding of French or English

You may not qualify if:

  • the index exacerbation is the first episode of wheezing in the previous year,
  • there is co-existence of other chronic pulmonary (such as Bronchopulmonary dysplasia (BPD), cystic fibrosis (CF)), renal or cardiac diseases;

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ste-Justine Hospital

Montreal, Quebec, H3T 1C5, Canada

Location

MeSH Terms

Conditions

AsthmaTreatment Adherence and Compliance

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System DiseasesHealth BehaviorBehavior

Study Officials

  • Francine M. Ducharme, MD, MSc

    CHUS-Ste Justine Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Francine Ducharme

Study Record Dates

First Submitted

October 12, 2005

First Posted

October 14, 2005

Study Start

August 1, 2002

Primary Completion

April 1, 2007

Study Completion

December 1, 2011

Last Updated

April 20, 2017

Record last verified: 2017-04

Locations