NCT00232388

Brief Summary

The purpose of this study is to determine if the carboxy-terminal of procollagen type I (PICP) can be a useful marker of different degrees of myocardial fibrosis.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
45

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Sep 2005

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2005

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

October 3, 2005

Completed
1 day until next milestone

First Posted

Study publicly available on registry

October 4, 2005

Completed
1.9 years until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2007

Completed
Last Updated

October 7, 2015

Status Verified

October 1, 2015

First QC Date

October 3, 2005

Last Update Submit

October 6, 2015

Conditions

Systolic Dysfunction

Keywords

Ejection Fraction <35%

Outcome Measures

Primary Outcomes (1)

  • There will be a significant relationship between the severity of diastolic dysfunction and PICP

Interventions

Blood drawPROCEDURE

Eligibility Criteria

Age18 Years - 100 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Persons with left ventricular systolic dysfunction from the Texas Tech University Health Sciences Center outpatient clinic and University Medical Center, Lubbock, Texas

You may qualify if:

  • Evidence of left ventricular systolic dysfunction (measured LVEF% less than 35%) measured by echocardiography within the previous three months at the time of enrollment
  • Greater than or equal to 18 years of age
  • Greater than or equal to 110 pounds in weight

You may not qualify if:

  • Non-sinus rhythm at the time of enrollment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

TTUHSC

Lubbock, Texas, 79430, United States

Location

Biospecimen

Retention: NONE RETAINED

PLEASE NOTE THAT THE INVESTIGATOR LEFT THE INSTITUION WITHOUT PROVIDING ANY INFORMATION REGARDING THIS PROJECT. NO FORWARDING INFORMATION IS AVAILABLE FROM THE INVESTIGATOR.

MeSH Terms

Interventions

Blood Specimen Collection

Intervention Hierarchy (Ancestors)

Specimen HandlingClinical Laboratory TechniquesDiagnostic Techniques and ProceduresDiagnosisPuncturesSurgical Procedures, OperativeInvestigative Techniques

Study Officials

  • Chanwit Roongsritong, MD

    TTUHSC

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Sponsor Type
OTHER

Study Record Dates

First Submitted

October 3, 2005

First Posted

October 4, 2005

Study Start

September 1, 2005

Study Completion

September 1, 2007

Last Updated

October 7, 2015

Record last verified: 2015-10

Locations

US(1)