NCT00231504

Brief Summary

The deficit in the total number of antral follicles is associated with a reduction of the ovarian fertility potential in young women. The principal objective of this study is to evaluate the relationship between FSH receptor polymorphism and antral follicle count. The investigators have designed a study of FSH receptor polymorphisms P1 and P2 as an association with a low antral follicle count in the ovary.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
82

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Oct 2005

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2005

Completed
2 days until next milestone

First Submitted

Initial submission to the registry

October 3, 2005

Completed
1 day until next milestone

First Posted

Study publicly available on registry

October 4, 2005

Completed
3.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2009

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2009

Completed
Last Updated

January 6, 2010

Status Verified

March 1, 2007

Enrollment Period

3.4 years

First QC Date

October 3, 2005

Last Update Submit

January 5, 2010

Conditions

Antral Follicle DeficitFertility

Keywords

Polymorphism P1Polymorphism P2FSH ReceptorAntral follicle countFSH receptor polymorphism

Interventions

Blood samplesPROCEDURE

Blood samples

Eligibility Criteria

Age18 Years - 35 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

YOUNG WOMAN

You may qualify if:

  • to 35 years old
  • to 9 or 13 to 20 antral follicles
  • Caucasian, occidental Europe
  • Presence of both ovaries
  • Informed consent

You may not qualify if:

  • Ovarian anomalies
  • Menopause
  • Pregnancy
  • Other diseases

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Antoine Beclere Hospital, Obstetrics and Gynaecology and Reproduction Medicine Service

Paris, 92140, France

Location

Biospecimen

Retention: SAMPLES WITH DNA

DNA

MeSH Terms

Interventions

Blood Specimen Collection

Intervention Hierarchy (Ancestors)

Specimen HandlingClinical Laboratory TechniquesDiagnostic Techniques and ProceduresDiagnosisPuncturesSurgical Procedures, OperativeInvestigative Techniques

Study Officials

  • Renato FANCHIN, MD

    Assistance Publique - Hôpitaux de Paris

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

October 3, 2005

First Posted

October 4, 2005

Study Start

October 1, 2005

Primary Completion

March 1, 2009

Study Completion

May 1, 2009

Last Updated

January 6, 2010

Record last verified: 2007-03

Locations

FR(1)