NCT00228202

Brief Summary

The researchers select 100 cytomegalovirus (CMV) DNA samples from patients diagnosed with CMV infection. Patients include bone marrow transplant patients, pregnant women and newborns. The researchers determine viral load by real-time polymerase chain reaction (PCR). They amplify CMV-gB sequences by PCR and type by sequencing and restriction fragment length polymorphism (RFLP). The researchers obtain clinical data from patients' records. They examine association between patients' clinical status and CMV-gB genotype and viral load.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2005

Completed
25 days until next milestone

First Submitted

Initial submission to the registry

September 26, 2005

Completed
2 days until next milestone

First Posted

Study publicly available on registry

September 28, 2005

Completed
Last Updated

August 18, 2006

Status Verified

January 1, 2006

First QC Date

September 26, 2005

Last Update Submit

August 17, 2006

Conditions

Cytomegalovirus Infections

Keywords

cytomegalovirusCMVpregnancyamniotic fluidbone marrowtransplantationviral loadglycoprotein BgenotypingPCRreal-time PCRCMV diseaseCongenital CMV infection

Eligibility Criteria

Age0 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • CMV DNA sample from a transplant patient with CMV disease.
  • CMV DNA from amniotic fluid of women with CMV infection
  • CMV DNA from urine of newborns with congenital defects compatible with CMV.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Central Virology Laboratory, Chaim Sheba Medical Center Tel-Hashomer

Ramat Gan, 52621, Israel

RECRUITING

MeSH Terms

Conditions

Cytomegalovirus Infections

Condition Hierarchy (Ancestors)

Herpesviridae InfectionsDNA Virus InfectionsVirus DiseasesInfections

Study Officials

  • Naty Keller, MD/PhD

    Sheba Medical Center

    STUDY DIRECTOR

Central Study Contacts

Ella Mendelson, PhD

CONTACT

972-3-530-2421ellamen@sheba.health.gov.il

Naty Keller, MD/PhD

CONTACT

972-3-530-2304kelern@sheba.health.gov.il

Study Design

Study Type
observational
Observational Model
NATURAL HISTORY
Time Perspective
OTHER
Sponsor Type
OTHER GOV

Study Record Dates

First Submitted

September 26, 2005

First Posted

September 28, 2005

Study Start

September 1, 2005

Last Updated

August 18, 2006

Record last verified: 2006-01

Locations

IL(1)