NCT00213733

Brief Summary

This is a prospective study of surgically resected samples and lymph nodes of lung cancer patients. For histopathologically positive lymph nodes from a complete resection, the investigators would like to analyse tumor tissue by allelotyping and comparing these results with those observed in the primary lung tumor to establish a cartography of molecular alteration in resected lung cancer. For non histopathologically positive lymph nodes, the investigators would like to research the presence (or not) of micrometastasis by allele-specific PCR (polymerase chain reaction).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
150

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jun 2004

Longer than P75 for all trials

Geographic Reach
1 country

5 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2004

Completed
1.3 years until next milestone

First Submitted

Initial submission to the registry

September 13, 2005

Completed
8 days until next milestone

First Posted

Study publicly available on registry

September 21, 2005

Completed
5.9 years until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2011

Completed
Last Updated

August 30, 2011

Status Verified

August 1, 2011

First QC Date

September 13, 2005

Last Update Submit

August 29, 2011

Conditions

Lung Cancer

Keywords

Lung cancer patientsnon-small cell lung cancermolecular markerlymph node completed resectedLung cancer samples and paired lymph node resected

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with resectable non-small cell lung cancer (stage I to IIIA), with a complete resection of the tumor and paired lymph nodes

You may qualify if:

  • Patients with resectable non-small cell lung cancer (stage I to IIIA), with a complete resection of the tumor and paired lymph nodes.
  • Informed consent is required.

You may not qualify if:

  • Another cancer
  • Chemotherapy before surgical treatment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (5)

Service de Chirurgie Thoracique, Hôpital Civil

Strasbourg, 67091, France

Location

Service de Pneumologie, Hôpital Lyautey

Strasbourg, 67091, France

Location

Laboratoire de Biochimie et de Biologie Moléculaire, Hôpital de Hautepierre

Strasbourg, 67098, France

Location

Service d'Anatomie Pathologique, Hôpital de Hautepierre

Strasbourg, 67098, France

Location

Service de Pneumologie, Hôpital de Hautepierre

Strasbourg, 67098, France

Location

MeSH Terms

Conditions

Lung NeoplasmsCarcinoma, Non-Small-Cell Lung

Condition Hierarchy (Ancestors)

Respiratory Tract NeoplasmsThoracic NeoplasmsNeoplasms by SiteNeoplasmsLung DiseasesRespiratory Tract DiseasesCarcinoma, BronchogenicBronchial Neoplasms

Study Officials

  • Michèle BEAU-FALLER, MD

    Laboratoire de Biochimie et de Biologie Moléculaire, Hôpital de Hautepierre

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 13, 2005

First Posted

September 21, 2005

Study Start

June 1, 2004

Study Completion

August 1, 2011

Last Updated

August 30, 2011

Record last verified: 2011-08

Locations

FR(5)