Acute, Affective, Organic Disorders.

NCT00201474 | Completed

• 1 other identifier: AEV-98
• Study Type: observational
• Target: 32
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of the study is to investigate whether patients with brief depressive periods together with other fluctuating psychiatric symptoms, have this condition due to epilepsy or an other organic brain disorder.

Conditions

Depressive Disorders

Keywords

brief depressive episodes; affective disorders; EEG and QEEG; epilepsy; organic brain disorders; acute psychiatry

Outcome Measures

Primary Outcomes (1)

• epilepsy or an other organic brain disorder

  EEG and QEEG are taken three times in the first week

  1 week

Study Arms (2)

brief depressive periods

brief depressive periods together with other fluctuating psychiatric symptoms

major depressive disorder

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Study and control groups both from a psychiatric acute ward. The patients are acutely admitted suffering from different types of depressive symptoms.

You may qualify if:

• Acutely admitted psychiatric patients who have at different times the last 2 weeks filled criteria for at least two new DSM-4 Axis 1 psychiatric diagnoses. One of them has to be a depressive episode (MADRS\>20)

You may not qualify if:

• Patients not speaking Norwegian or English.
• Patients not willing to participate.
• Patients with dementia or mental retardation to an extensive degree.

Sponsors & Collaborators

• Norwegian University of Science and Technology: lead
• St. Olavs Hospital: collaborator
• Dr. Dedichens Institute for Psychiatric Research, Oslo, Norway.: collaborator
• GlaxoSmithKline: collaborator

Study Sites (1)

Østmarka Psychiatric Department, St. Olavs Hospital

Trondheim, 7441, Norway

Location

Related Publications (2)

• Vaaler AE, Morken G, Iversen VC, Kondziella D, Linaker OM. Acute Unstable Depressive Syndrome (AUDS) is associated more frequently with epilepsy than major depression. BMC Neurol. 2010 Jul 30;10:67. doi: 10.1186/1471-2377-10-67.

  PMID: 20673344 RESULT

• Vaaler AE, Morken G, Linaker OM, Sand T, Kvistad KA, Brathen G. Symptoms of epilepsy and organic brain dysfunctions in patients with acute, brief depression combined with other fluctuating psychiatric symptoms: a controlled study from an acute psychiatric department. BMC Psychiatry. 2009 Sep 30;9:63. doi: 10.1186/1471-244X-9-63.

  PMID: 19793395 DERIVED

Biospecimen

Retention: SAMPLES WITHOUT DNA

Ordinary laboratory tests, medication, substances.

MeSH Terms

Conditions

Depressive Disorder; Mood Disorders; Epilepsy

Condition Hierarchy (Ancestors)

Mental Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases

Study Officials

• Olav M Linaker, Professor

  Norwegian University of Science and Technology

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: September 16, 2005
• First Posted: September 20, 2005
• Study Start: October 1, 1998
• Primary Completion: October 1, 2004
• Study Completion: June 1, 2010
• Last Updated: August 4, 2016

Record last verified: 2016-08

Locations

NO (1)