Psychosocial Determinants of Medication Adherence in Hypertensive African Americans

NCT00195182 | Unknown DMC

• 1 other identifier: 0302006001
• Study Type: observational
• Target: 262
• Locations: 1 country
• Sites: 1

Brief Summary

The specific aims for this study are:

1. 1.To examine the relationship between perceived racism and medication adherence among hypertensive African-American patients.
2. 2.To determine if psychological stress and depression mediate the relationship between perceived racism and medication adherence.

Conditions

Hypertension

Keywords

Hypertension; African-American; Perceived Racism; Psychological Stress; Medication Adherence

Outcome Measures

Primary Outcomes (1)

• To evaluate intervention of induced positive affect and induced self-affirmation will increase medication adherence among African-American hypertensive patients.

  every two months for one year

Study Arms (2)

1. No intervention

This group received follow-up every 2-months for one year. Follow-up included questions about their blood pressure and how well they had been able to adhere to their medication goal.

Behavioral: Self affirmation and positive affect induction vs. control

2. Experimental

This group received follow-up every 2-months for one year. Follow-up included questions about their blood pressure and how well they had been able to engage adhere to their medication goal. The intervention included receiving an additional educational workbook about using positive affect and self affirmation, as well as participating in using positive affect and self-affirmation to motivate behavior change, which in this case was to increase their physical activity level.

Behavioral: Self affirmation and positive affect induction vs. control

Interventions

Self affirmation and positive affect induction vs. control BEHAVIORAL

During the physical activity goal setting process, subjects were randomly assigned to either the control or the intervention group. The intervention included receiving an additional educational workbook about using positive affect and self affirmation, as well as participating in using positive affect and self-affirmation to motivate behavior change, which in this case was to increase their medication adherence. Patient also received small token gifts to remind them of their participation in the study and to induce positive affect. The control group also set a physical activity goal and received the same follow-up, but did not participate in the positive affect and self-affirmation portion.

1. No intervention; 2. Experimental

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Hypertensive African Americans

You may qualify if:

• Patients must be self-identified as African American.
• All patients must be aged 18 years or older.
• All patients must be diagnosed as having hypertension (for this project, hypertension will be defined according to the widely accepted criteria of the 6th Joint National Committee Guidelines on Prevention, Detection, Evaluation and Treatment of Hypertension, specifically a systolic blood pressure \>140 mm hg or a diastolic blood pressure \>90 mm hg) or if patients are taking any prescribed anti-hypertensive medication.
• Patients must be able to provide informed consent in English.

You may not qualify if:

• Patients who are unable to walk several blocks for any reason.
• Patients who refused to participate.
• Patients who are unable to provide informed consent.

Sponsors & Collaborators

• Weill Medical College of Cornell University: lead
• National Heart, Lung, and Blood Institute (NHLBI): collaborator

Study Sites (1)

New York Presbyterian Hospital-Weill Medical College

New York, New York, 10021, United States

Location

Related Publications (1)

• Ravenell JE, Charlson ME. Stressed out: Definitions of stress among hypertensive African American men. Journal of General Internal Medicine 20(S1):128, 2005.

  BACKGROUND

MeSH Terms

Conditions

Hypertension; Stress, Psychological; Medication Adherence

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases; Behavioral Symptoms; Behavior; Patient Compliance; Patient Acceptance of Health Care; Treatment Adherence and Compliance; Health Behavior

Study Officials

• Joseph E Ravenell, MD, MS

  University of Texas Southwestern Medical Center

  PRINCIPAL INVESTIGATOR

• Mary E Charlson, MD

  Weill Medical College of Cornell University

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: September 14, 2005
• First Posted: September 19, 2005
• Study Start: September 1, 2003
• Study Completion: June 1, 2008
• Last Updated: May 21, 2008

Record last verified: 2008-05

Locations

US (1)