Light Based Analysis of Developing Breast Tissue in Adolescent Girls: a Feasibility Study
Pilot Study to Investigate the Feasibility of Optical Spectroscopy to Quantify Bulk Breast Tissue Properties in Girls Age 10 - 14 Years
2 other identifiers
observational
20
1 country
1
Brief Summary
The proposed pilot study attempts to investigate the feasibility of Optical Spectroscopy (OS) as a method to quantify breast tissue composition and density in adolescent females. Our goals include: to assess whether adolescent girls can be instructed to assist with the OS measurement procedure and to determine the OS technique's ability to show breast tissue composition and density in adolescent breast tissue.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Apr 2005
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 1, 2005
CompletedFirst Submitted
Initial submission to the registry
September 9, 2005
CompletedFirst Posted
Study publicly available on registry
September 16, 2005
CompletedStudy Completion
Last participant's last visit for all outcomes
November 1, 2008
CompletedNovember 25, 2008
November 1, 2008
September 9, 2005
November 21, 2008
Conditions
Keywords
Eligibility Criteria
Residents of Toronto, Ontario, Canada.
You may qualify if:
- Are in good health and are able to provide assent
- Are between the ages of 10 and 14
- Are interested in participating in this study
- Are willing to come, accompanied by a parent, to the Princess Margaret Hospital
- Are able to provide consent
- Are willing to accompany your daughter to the Princess Margaret Hospital for one visit of about 45 minutes
You may not qualify if:
- Have had previous surgeries to the chest area
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University Health Network / Princess Margaret Hospital
Toronto, Ontario, M5G 2M9, Canada
Related Publications (4)
Blyschak K, Simick M, Jong R, Lilge L. Classification of breast tissue density by optical transillumination spectroscopy: optical and physiological effects governing predictive value. Med Phys. 2004 Jun;31(6):1398-414. doi: 10.1118/1.1738191.
PMID: 15259643BACKGROUNDSimick MK, Jong R, Wilson B, Lilge L. Non-ionizing near-infrared radiation transillumination spectroscopy for breast tissue density and assessment of breast cancer risk. J Biomed Opt. 2004 Jul-Aug;9(4):794-803. doi: 10.1117/1.1758269.
PMID: 15250768BACKGROUNDBlackmore KM, Knight JA, Jong R, Lilge L. Assessing breast tissue density by transillumination breast spectroscopy (TIBS): an intermediate indicator of cancer risk. Br J Radiol. 2007 Jul;80(955):545-56. doi: 10.1259/bjr/26858614. Epub 2007 May 30.
PMID: 17537757BACKGROUNDSimick MK, Lilge L. Optical transillumination spectroscopy to quantify parenchymal tissue density: an indicator for breast cancer risk. Br J Radiol. 2005 Nov;78(935):1009-17. doi: 10.1259/bjr/14696165.
PMID: 16249602BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Lothar Lilge, PhD
Ontario Cancer Institute, University Health Network, Toronto, Ontario, Canada M5G 2M9; Department of Biophysics and Bioimaging, University of Toronto, Toronto, Ontario, Canada M5G 2M9
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
September 9, 2005
First Posted
September 16, 2005
Study Start
April 1, 2005
Study Completion
November 1, 2008
Last Updated
November 25, 2008
Record last verified: 2008-11