Magnetic Resonance (MR) in Asthmatic Patients

NCT00188487 | Terminated Phase 1

• 1 other identifier: 05-0174
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

Asthma is a disease of small airways. Affected areas have reduced lung ventilation causing reflex vasoconstriction. MR perfusion imaging of the lungs is a sensitive method of imaging zonal lung perfusion.

Conditions

Asthma

Outcome Measures

Primary Outcomes (1)

• The correlation of MR lung perfusion analysis with computed tomography (CT) findings and pulmonary function tests

Interventions

magnetic resonance imaging (MRI) of the thorax DEVICE

Eligibility Criteria

• Age: 16 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• All asthmatic patients are eligible.

You may not qualify if:

• Patients in whom MRI is contraindicated

Sponsors & Collaborators

• University Health Network, Toronto: lead

Study Sites (1)

Toronto General Hospital

Toronto, Ontario, Canada

Location

MeSH Terms

Conditions

Asthma

Interventions

Magnetic Resonance Imaging

Condition Hierarchy (Ancestors)

Bronchial Diseases; Respiratory Tract Diseases; Lung Diseases, Obstructive; Lung Diseases; Respiratory Hypersensitivity; Hypersensitivity, Immediate; Hypersensitivity; Immune System Diseases

Intervention Hierarchy (Ancestors)

Tomography; Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis

Study Officials

• Narinder Paul, FRCP C

  University Health Network, Toronto

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: phase 1
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: September 12, 2005
• First Posted: September 16, 2005
• Study Start: September 1, 2005
• Study Completion: December 1, 2005
• Last Updated: June 17, 2024

Record last verified: 2024-06

Locations

CA (1)