NCT00183716

Brief Summary

This study will determine the effectiveness of the Trauma Recovery and Empowerment Model in reducing the severity of post-traumatic stress disorder symptoms in women with mental disorders and who have experienced sexual or physical abuse.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
300

participants targeted

Target at P50-P75 for phase_3

Timeline
Completed

Started Apr 2004

Typical duration for phase_3

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2004

Completed
1.5 years until next milestone

First Submitted

Initial submission to the registry

September 14, 2005

Completed
2 days until next milestone

First Posted

Study publicly available on registry

September 16, 2005

Completed
2.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2007

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2007

Completed
Last Updated

July 23, 2012

Status Verified

July 1, 2012

Enrollment Period

3.6 years

First QC Date

September 14, 2005

Last Update Submit

July 20, 2012

Conditions

Keywords

PTSDPhysical AbuseSexual AbuseWomenTraumaGroup TherapySubstance Abuse

Outcome Measures

Primary Outcomes (1)

  • PTSD symptom severity

    Measured at baseline and Months 6, 12, and 18

Secondary Outcomes (4)

  • Distorted beliefs

    Measured at baseline and Months 6, 12, and 18

  • Depressive symptoms

    Measured at baseline and Months 6, 12, and 18

  • Substance use

    Measured at baseline and Months 6, 12, and 18

  • Mental health service utilization

    Measured at Months 6, 12, and 18

Study Arms (2)

1

EXPERIMENTAL

Participants will receive Trauma Recovery and Empowerment Model and usual care

Behavioral: Trauma Recovery and Empowerment Model (TREM)Behavioral: Usual care

2

ACTIVE COMPARATOR

Participants will receive usual care

Behavioral: Usual care

Interventions

TREM is a 29-session group intervention for women who have experienced psychological trauma (e.g., childhood physical or sexual abuse), focusing on skill development, understanding the effects of trauma, and empowerment.

1
Usual careBEHAVIORAL

Participants will receive usual care for women who have experienced psychological trauma.

12

Eligibility Criteria

Age20 Years - 60 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • History of physical and/or sexual abuse
  • Diagnosis of a severe mental disorder
  • Diagnosis of PTSD with a symptom severity score of 21 or higher

You may not qualify if:

  • Severe developmental disabilities or organic brain damage

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Community Connections

Washington D.C., District of Columbia, 20003, United States

Location

The North Baltimore Center

Baltimore, Maryland, 21218, United States

Location

MeSH Terms

Conditions

Stress Disorders, Post-TraumaticMental DisordersDepressionWounds and InjuriesSubstance-Related Disorders

Condition Hierarchy (Ancestors)

Stress Disorders, TraumaticTrauma and Stressor Related DisordersBehavioral SymptomsBehaviorChemically-Induced Disorders

Study Officials

  • Gregory J. McHugo, PhD

    Dartmouth College

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 14, 2005

First Posted

September 16, 2005

Study Start

April 1, 2004

Primary Completion

November 1, 2007

Study Completion

November 1, 2007

Last Updated

July 23, 2012

Record last verified: 2012-07

Locations