Prolonged Exposure Therapy Versus Active Psychotherapy in Treating Post-Traumatic Stress Disorder in Adolescents
Treating Terror-Related PTSD in Adolescents
2 other identifiers
interventional
60
1 country
1
Brief Summary
This study will compare the effectiveness of prolonged exposure therapy versus active psychotherapy in treating post-traumatic stress disorder (PTSD) in adolescents.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for phase_1
Started Sep 2004
Typical duration for phase_1
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 1, 2004
CompletedFirst Submitted
Initial submission to the registry
September 13, 2005
CompletedFirst Posted
Study publicly available on registry
September 16, 2005
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2008
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2008
CompletedDecember 12, 2008
December 1, 2008
3.5 years
September 13, 2005
December 11, 2008
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Symptoms of post-traumatic stress disorder
Measured at Month 3
Symptoms of depression
Measured at Month 3
Secondary Outcomes (1)
Clinical global assessment of overall functioning
Measured at Month 3
Study Arms (2)
1
EXPERIMENTALParticipants receiving prolonged exposure therapy
2
ACTIVE COMPARATORParticipants receiving active psychotherapy
Interventions
Prolonged exposure therapy includes a trauma focused protocol and cognitive behavioral treatment for PTSD. Cognitive behavioral treatment includes psychoeducation, in vivo exposures, and imaginal exposures.
Active psychotherapy includes non-trauma focused therapy, based on time-limited psychodynamic treatment, which includes a formulation of a central issue and open-associative sessions exploring main conflicts and drives.
Eligibility Criteria
You may qualify if:
- Primary diagnosis of PTSD
- In grades 6-12
- No change in medication regimen for more than 6 weeks
You may not qualify if:
- Diagnosis of ADHD, conduct disorder, thought disorder, or bipolar disorder
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Schneider Children's Medical Center of Israel
Petach Tikvah, 49202, Israel
Related Publications (1)
Gilboa-Schechtman E, Foa EB, Shafran N, Aderka IM, Powers MB, Rachamim L, Rosenbach L, Yadin E, Apter A. Prolonged exposure versus dynamic therapy for adolescent PTSD: a pilot randomized controlled trial. J Am Acad Child Adolesc Psychiatry. 2010 Oct;49(10):1034-42. doi: 10.1016/j.jaac.2010.07.014. Epub 2010 Sep 6.
PMID: 20855048DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Eva Gilboa-Schechtman, PhD
Bar Ilan University
- PRINCIPAL INVESTIGATOR
Edna B. Foa, PhD
University of Pennsylvania
Study Design
- Study Type
- interventional
- Phase
- phase 1
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- NIH
Study Record Dates
First Submitted
September 13, 2005
First Posted
September 16, 2005
Study Start
September 1, 2004
Primary Completion
March 1, 2008
Study Completion
June 1, 2008
Last Updated
December 12, 2008
Record last verified: 2008-12