NCT00181857

Completed

Risk of Attention Deficit Hyperactivity Disorder (ADHD) in t...

Massachusetts General Hospital Source

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Other study identifiers

Sponsor study identifier

2004-P-002687

Study Type

observational

Actual enrollment (reported)

58

Locations

1 country

Sites

1

Timeline

Study Start

February 2005

Date type not reported

This date has not been verified as actual or estimated.

Primary Completion

February 2006

Actual (reported)

Study Completion

February 2008

Actual (reported)

Brief Summary

The researchers plan to explore the validity of the category of ADHD NOS by identifying the risk for ADHD in the children of ADHD NOS adult probands and identifying common correlates of ADHD in these children. The researchers hypothesize that the rate of ADHD will be higher in the children of the ADHD NOS probands than the rate of ADHD previously published for siblings of proband children with ADHD; and ADHD children of ADHD NOS adults will have higher rates of school failure (as measured by their rate of repeated grades, need for tutoring, and placement in special classes) than their non-ADHD siblings.

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: completed
Actual enrollment (reported): 58 participants
Study completion date: February 2008
Actual (reported)
Listed locations: 1 countries · 1 sites

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

Study Start
February 2005
Date type not reported
This date has not been verified as actual or estimated.
First Submitted
September 13, 2005
Actual (reported)
First Posted
September 16, 2005
Actual (reported)
Primary Completion
February 2006
Actual (reported)
Study Completion
February 2008
Actual (reported)

Last Updated: October 31, 2013
Status Verified: October 2013
Last Update Submitted: October 30, 2013

Conditions

ADHD

Keywords

ADHD NOSfamilial riskchildren

Outcome Measures

Primary Outcomes (1)

ADHD Diagnosis
at evaluation

Study Arms (1)

1

Children of Adults with ADHD NOS

Eligibility Criteria

Age18 Years+

Sexall

Healthy VolunteersYes

Age GroupsAdult (18-64), Older Adult (65+)

Sampling MethodNon-Probability Sample

Study Population

Children of Adults with ADHD NOS

You may qualify if:

Must be a biological child of an ADHD NOS proband. The proband must meet the following criterion:

Sponsors & Collaborators

Massachusetts General Hospital
Otherlead

Study Sites (1)

Massachusetts General Hospital

Boston, Massachusetts, 02114, United States

MeSH Terms

Conditions

Attention Deficit Disorder with Hyperactivity

Condition Hierarchy (Ancestors)

Attention Deficit and Disruptive Behavior DisordersNeurodevelopmental DisordersMental Disorders

Study Officials

Craig Surman, MD
Massachusetts General Hospital
PRINCIPAL INVESTIGATOR

Enrollment

58 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: FAMILY BASED
Time Perspective: CROSS SECTIONAL
Sponsor Type: OTHER
Responsible Party: PRINCIPAL INVESTIGATOR
PI Title: Scientific Director of the Adult ADHD Program, Clinical and Research Program in Pediatric Psychopharmacology and Adult ADHD

Study Record Dates

First Submitted

September 13, 2005

First Posted

September 16, 2005

Study Start

February 2005

Date type not reported

This date has not been verified as actual or estimated.

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Age: above 18 years

Sex: male or female

Intelligence quotient (IQ) above 80

Met criteria for the diagnosis of attention deficit hyperactivity disorder not otherwise specified (ADHD NOS), by the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), as manifested in clinical evaluation and confirmed by structured interview. This is operationalized by either:

having at least 6 out of 9 current DSM-IV items of either inattention or hyperactivity/impulsivity but \< 5 items from either list in childhood, or

having 5 out of 9 current DSM-IV items of either inattention or hyperactivity/impulsivity, but not having the 6 current symptoms in either category. This second category will be included independent of the presence or absence of ADHD symptoms in childhood.

Had a Clinical Global Impression: ADHD score of 4 (moderately ill) or higher illness severity at a clinical evaluation.

Has at least one biological offspring

You may not qualify if:

No adequate informant is available to answer the survey questions.
Sensorimotor deficits. (These include deficits that would impede the survey process, e.g. profound deafness, blindness, inadequate command of the English language, or profound disorders of language.)
Psychosis, autism, schizophrenia.

Contact the study team to confirm eligibility.

Primary Completion

February 2006

Actual (reported)

Study Completion

February 2008

Actual (reported)

Last Updated

October 31, 2013

Record last verified: 2013-10

Source record

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Source: ClinicalTrials.gov.

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Registry identifier: NCT00181857
Data provider: ClinicalTrials.gov
Source updated: 2013-10-31
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:20:59 UTC

Locations

US(1)

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Study Arms (1)

1

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations