NCT00174551

Brief Summary

Investigating the effect of prazosin for nighttime symptoms of civilian Posttraumatic Stress Disorder.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Nov 2003

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2003

Completed
1.9 years until next milestone

First Submitted

Initial submission to the registry

September 9, 2005

Completed
6 days until next milestone

First Posted

Study publicly available on registry

September 15, 2005

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2005

Completed
Last Updated

September 11, 2006

Status Verified

September 1, 2005

First QC Date

September 9, 2005

Last Update Submit

September 7, 2006

Conditions

Stress Disorders, Post-Traumatic

Outcome Measures

Primary Outcomes (4)

  • Sleep time

  • REM sleep time

  • Nightmare frequency

  • CGI

Secondary Outcomes (2)

  • Distressed Awakenings frequency

  • PCL-C

Interventions

prazosinDRUG

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • must meet DSM-IV criterion for PTSD

You may not qualify if:

  • Must not have untreated sleep apnea

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Fletcher B. Taylor

Tacoma, Washington, 98467, United States

Location

MeSH Terms

Conditions

Stress Disorders, Post-Traumatic

Interventions

Prazosin

Condition Hierarchy (Ancestors)

Stress Disorders, TraumaticTrauma and Stressor Related DisordersMental Disorders

Intervention Hierarchy (Ancestors)

QuinazolinesHeterocyclic Compounds, 2-RingHeterocyclic Compounds, Fused-RingHeterocyclic Compounds

Study Officials

  • Fletcher B Taylor, M.D.

    Rainier Associates

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 9, 2005

First Posted

September 15, 2005

Study Start

November 1, 2003

Study Completion

November 1, 2005

Last Updated

September 11, 2006

Record last verified: 2005-09

Locations

US(1)