NCT00174330

Brief Summary

To evaluate efficacy of the dual therapy of atorvastatin + amlodipine vs. amlodipine alone .

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
330

participants targeted

Target at P50-P75 for phase_4 hypertension

Timeline
Completed

Started May 2005

Shorter than P25 for phase_4 hypertension

Geographic Reach
1 country

15 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2005

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

September 9, 2005

Completed
6 days until next milestone

First Posted

Study publicly available on registry

September 15, 2005

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2006

Completed
Last Updated

January 27, 2021

Status Verified

January 1, 2021

First QC Date

September 9, 2005

Last Update Submit

January 26, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • To evaluate efficacy of the dual therapy of atorvastatin 10mg or 20mg + amlodipine 5mg or 10mg vs. amlodipine 5mg or 10mg alone

Secondary Outcomes (1)

  • To provide comparative evaluation of the safety profile of the dual therapy with atorvastatin + amlodipine versus amlodipine alone.

Interventions

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Subjects with a diagnosis of both hyperlipidemia and hypertension.

You may not qualify if:

  • Subjects with Type 1 diabetes mellitus or Type 2 diabetes mellitus.
  • Subjects with other atherosclerotic disease.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (15)

Pfizer Investigational Site

Beijing, Beijing Municipality, 100044, China

Location

Pfizer Investigational Site

Guangzhou, Guangdong, 510080, China

Location

Pfizer Investigational Site

Guangzhou, Guangdong, 510100, China

Location

Pfizer Investigational Site

Guangzhou, Guangdong, 510515, China

Location

Pfizer Investigational Site

Nanjing, Jiangsu, 210029, China

Location

Pfizer Investigational Site

Shenyang, Liaoning, 110016, China

Location

Pfizer Investigational Site

Shanghai, Shanghai Municipality, 200032, China

Location

Pfizer Investigational Site

Hangzhou, Zhejiang, 310016, China

Location

Pfizer Investigational Site

Beijing, 100029, China

Location

Pfizer Investigational Site

Beijing, 100083, China

Location

Pfizer Investigational Site

Beijing, China

Location

Pfizer Investigational Site

Shanghai, 200003, China

Location

Pfizer Investigational Site

Shanghai, 200025, China

Location

Pfizer Investigational Site

Shanghai, 200233, China

Location

Pfizer Investigational Site

Tianjin, 300211, China

Location

Related Links

MeSH Terms

Conditions

HypertensionHyperlipidemias

Interventions

AtorvastatinAmlodipine

Condition Hierarchy (Ancestors)

Vascular DiseasesCardiovascular DiseasesDyslipidemiasLipid Metabolism DisordersMetabolic DiseasesNutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

PyrrolesAzolesHeterocyclic Compounds, 1-RingHeterocyclic CompoundsHeptanoic AcidsFatty AcidsLipidsDihydropyridinesPyridines

Study Officials

  • Pfizer CT.gov Call Center

    Pfizer

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY

Study Record Dates

First Submitted

September 9, 2005

First Posted

September 15, 2005

Study Start

May 1, 2005

Study Completion

February 1, 2006

Last Updated

January 27, 2021

Record last verified: 2021-01

Locations