NCT00173927

Brief Summary

The goals of this trial are:

  1. 1.To compare the sensitivity and specificity of various tools including Doppler and magnetic resonance imaging (MRI) for diagnosing vertebral artery stenosis and carotid artery stenosis. The positron emission tomography (PET)/MRI fusion imaging will be a promising tool to provide both anatomical and functional imaging for vulnerable plaques.
  2. 2.To identify patients at high risk of plaque rupture by image studies, biomedical profile, and gene expression of circulating monocytes.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2004

Completed
1.5 years until next milestone

First Submitted

Initial submission to the registry

September 12, 2005

Completed
3 days until next milestone

First Posted

Study publicly available on registry

September 15, 2005

Completed
Last Updated

October 30, 2007

Status Verified

September 1, 2005

First QC Date

September 12, 2005

Last Update Submit

October 29, 2007

Conditions

Extracranial Atherosclerosis

Keywords

extracranial atherosclerosisimagingbiomarkers

Eligibility Criteria

Age30 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with symptomatic extracranial atherosclerosis who are going to receive angiography and possible intervention.

You may not qualify if:

  • Acute systemic illness
  • Creatinine \> 3 mg/dl
  • Unable to tolerate the tests (including MRI and PET/computed tomography \[CT\] scans)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

National Taiwan University Hospital

Taipei, 10012, Taiwan

RECRUITING

Study Officials

  • Hsien-Li Kao, MD

    National Taiwan University Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Hsien-Li Kao, MD

CONTACT

886-2-2312-3456hsienli_kao@yahoo.com

Study Design

Study Type
observational
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 12, 2005

First Posted

September 15, 2005

Study Start

March 1, 2004

Last Updated

October 30, 2007

Record last verified: 2005-09

Locations

TW(1)