Pulmonary Rehabilitation in Interstitial Lung Disease
1 other identifier
interventional
56
1 country
2
Brief Summary
Interstitial lung disease (ILD) is a highly disabling group of conditions including idiopathic pulmonary fibrosis (IPF), acute and chronic interstitial pneumonias, connective tissue diseases and sarcoidosis. People with ILD frequently experience breathlessness on exertion, which limits their ability to undertake daily activities. People with ILD report very poor quality of life due to low levels of physical functioning and vitality, and high levels of breathlessness and fatigue. There are few treatments for ILD and those that are available have limited impact on quality of life. The aim of this study is to assess the effects of Pulmonary Rehabilitation, which consists of specialised exercise training for people with lung disease, on exercise capacity and quality of life in people with ILD. We hypothesis that exercise training will result in reduced dyspnoea, improved exercise tolerance and enhanced quality of life.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Mar 2005
Typical duration for not_applicable
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2005
CompletedFirst Submitted
Initial submission to the registry
September 13, 2005
CompletedFirst Posted
Study publicly available on registry
September 15, 2005
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2007
CompletedApril 5, 2007
April 1, 2007
September 13, 2005
April 4, 2007
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Functional exercise capacity
Secondary Outcomes (3)
Maximal exercise capacity
Health-related quality of life
Dyspnoea
Interventions
Eligibility Criteria
You may qualify if:
- Ambulant
- Stable medical therapy
- Dyspnoea on exertion following maximal treatment
You may not qualify if:
- A history of syncope on exertion
- Too unwell to attend the hospital for exercise training
- Any other comorbidities which would prevent exercise training
- Previous Pulmonary Rehabilitation in the last 12 months
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- The Alfredlead
- La Trobe Universitycollaborator
- Austin Hospital, Melbourne Australiacollaborator
- Victorian Tuberculosis and Lung Associationcollaborator
Study Sites (2)
Alfred Hospital
Melbourne, Victoria, 3004, Australia
Austin Hospital
Melbourne, Victoria, 3084, Australia
Related Publications (1)
Holland AE, Hill CJ, Conron M, Munro P, McDonald CF. Short term improvement in exercise capacity and symptoms following exercise training in interstitial lung disease. Thorax. 2008 Jun;63(6):549-54. doi: 10.1136/thx.2007.088070. Epub 2008 Feb 1.
PMID: 18245143DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Anne E Holland, PhD
Alfred Hospital and LaTrobe University
- PRINCIPAL INVESTIGATOR
Matthew Conron, MBBS
The Alfred
- PRINCIPAL INVESTIGATOR
Prue Munro, BAppSc
The Alfred
- PRINCIPAL INVESTIGATOR
Christine McDonald, MBBS PhD
Austin Hospital, Melbourne Australia
- PRINCIPAL INVESTIGATOR
Catherine Hill, PhD
Austin Hospital, Melbourne Australia
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
September 13, 2005
First Posted
September 15, 2005
Study Start
March 1, 2005
Study Completion
May 1, 2007
Last Updated
April 5, 2007
Record last verified: 2007-04