NCT00155922

Brief Summary

The investigators hypothesize that macrophages play a crucial role in the pathogenesis of atherosclerosis in patients with type 2 diabetes mellitus (T2DM).

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2003

Completed
1.9 years until next milestone

First Submitted

Initial submission to the registry

September 9, 2005

Completed
3 days until next milestone

First Posted

Study publicly available on registry

September 12, 2005

Completed
Last Updated

December 14, 2006

Status Verified

September 1, 2005

First QC Date

September 9, 2005

Last Update Submit

December 13, 2006

Conditions

Diabetes Mellitus, Type 2Atherosclerosis

Keywords

Diabetes mellitusMonocyteGene expressionMonocyte gene expression

Eligibility Criteria

Age25 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Normal control: fasting plasma glucose (FPG) less than 126 mg/dl.
  • T2DM: FPG \>＝126 mg/dl.
  • Group 1 (good glycemic control): HbA1c\<＝7% in the past 6 months
  • Group 2 (poor glycemic control): HbA1c\>＝8% in the past 6 months

You may not qualify if:

  • Acute systemic diseases

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

National Taiwan University Hospital

Taipei, 10012, Taiwan

RECRUITING

MeSH Terms

Conditions

Diabetes Mellitus, Type 2AtherosclerosisDiabetes Mellitus

Condition Hierarchy (Ancestors)

Glucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesArteriosclerosisArterial Occlusive DiseasesVascular DiseasesCardiovascular Diseases

Study Officials

  • Wei-Shiung Yang, MD, PhD

    National Taiwan University Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Wei-Shiung Yang, MD, PhD

CONTACT

886-2-2312-3456wsyang@ha.mc.ntu.edu.tw

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 9, 2005

First Posted

September 12, 2005

Study Start

November 1, 2003

Last Updated

December 14, 2006

Record last verified: 2005-09

Locations

TW(1)