Reducing the Risk of Developing Major Depression in Adolescents/Young Adults With Minor Depression/Depression Symptoms

NCT00145951 | Terminated

• 1 other identifier: 13798A
• Study Type: observational
• Target: 93
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this research study is to assess the feasibility of a combined primary care/web-based depression prevention intervention. Primary care physicians (PCP) currently lack an alternative behaviorally-based approach to antidepressant medications for individuals with depression symptoms or minor depression, but who have not yet developed Major Depression. The objective of this study is to compare the feasibility and efficacy of motivational interviewing (MI) versus brief advice in primary care to engage adolescents with a web-based depression prevention intervention.

Conditions

Depression

Study Arms (3)

1

2

3

Behavioral: motivational interviewing, brief advice in primary care

Interventions

motivational interviewing, brief advice in primary care BEHAVIORAL

motivational interviewing, brief advice in primary care

3

Eligibility Criteria

• Age: 14 Years - 75 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

* Subjects are between the ages of 14-18 years and * have one risk factor for developing depression in the next two years: * sub-clinical depressed mood (not meeting criteria of major depression), * a family history of depression in a parent or sibling, or * past personal history of depression or personal perception of risk depression and desire to participate

You may qualify if:

• (1) age 14-18 years and
• (2) one risk factor for developing depression in the next two years: sub-clinical depressed mood (not meeting criteria of major depression),
• a family history of depression in a parent or sibling, or past personal history of depression or personal perception of risk depression and desire to participate

You may not qualify if:

• criteria include meeting criteria or undergoing active treatment for major depression (5 or more symptoms nearly every day with functional impairment, minor depression),
• bipolar disorder,
• panic disorder,
• conduct disorder,
• substance abuse or having suicidal ideation.
• Active treatment for depression is defined as receiving anti-depressant medication or counseling within one year of remission of symptoms from the most recent episode.
• Those who meet DSM-IV criteria for minor depression (3-4 symptoms) or who report significant functional impairment (very difficult or above on the Prime MD functional impairment scale) will be notified and offered a referral for an evaluation by a mental health specialist (and will be strongly encouraged to attend).
• Those with 1-2 symptoms of depression will also be offered evaluation and treatment from a mental health specialist. In each case, the primary care physician will be notified and the parents (if under the age of 19).

Sponsors & Collaborators

• University of Chicago: lead

Study Sites (1)

University of Chicago

Chicago, Illinois, 60637, United States

Location

MeSH Terms

Conditions

Depression

Interventions

Motivational Interviewing; Crisis Intervention; Primary Health Care

Condition Hierarchy (Ancestors)

Behavioral Symptoms; Behavior

Intervention Hierarchy (Ancestors)

Directive Counseling; Counseling; Mental Health Services; Behavioral Disciplines and Activities; Health Services; Health Care Facilities Workforce and Services; Psychotherapy; Comprehensive Health Care; Patient Care Management; Health Services Administration

Study Officials

• Benjamin Van Voorhees, MD

  University of Chicago

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 1, 2005
• First Posted: September 5, 2005
• Study Start: May 1, 2006
• Primary Completion: September 1, 2007
• Study Completion: December 1, 2011
• Last Updated: March 28, 2014

Record last verified: 2014-03

Locations

US (1)