NCT00144443

Brief Summary

Objective: Our overall objective is to test the hypothesis that the health of children with chronic respiratory symptoms or chronic exposures to environmental hazards can be improved through a combination of standard home maintenance interventions and a set of interim controls and targeted repair interventions. I. Background: The Bi-State Kansas City Enhanced Enterprise Community (KCEEC) is one of pervasive poverty, unemployment and general distress. This same area is also an area of poor environmental health with a disproportionate number of children with lead poisoning, asthma, and home injuries. In May 2001, the Metropolitan (Kansas City) Health Council released a report urging the implementation of strategies to address this growing concern. They stated, "Environmental assessments and interventions in homes, schools, and workplaces are needed to promote indoor air quality and thereby help prevent asthma and asthma flare-ups," in combination with the need for, "trained community-based peer educators needed to work with families/communities in areas of high asthma incidence,". The need for major rehabilitation is echoed in the 1999 Consolidated Plan, as well as by most community development and housing officials. The KC CERT project responds to these concerns by demonstrating low-cost, replicable intervention strategies that can have an impact on the health and safety of children and their families. By providing training and employment opportunities to residents in high-risk areas to assess, prevent and remediate environmental hazards, this project promotes sustained systematic change within the KCEEC.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
200

participants targeted

Target at P50-P75 for not_applicable asthma

Timeline
Completed

Started Mar 2003

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2003

Completed
2.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2005

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

September 2, 2005

Completed
3 days until next milestone

First Posted

Study publicly available on registry

September 5, 2005

Completed
Last Updated

January 20, 2021

Status Verified

January 1, 2021

First QC Date

September 2, 2005

Last Update Submit

January 19, 2021

Conditions

AsthmaRhinitisAllergy

Keywords

AerobiologyAsthmaIndoor FungiAllergenHome Remediation

Outcome Measures

Primary Outcomes (2)

  • Reduction in home airborne fungal spore levels.

  • Reduction in home allergen exposure.

Secondary Outcomes (2)

  • Reduction in healthy care utilization

  • Improvement in quality of life

Interventions

Basic home repairBEHAVIORAL
Asthma Trigger EducationBEHAVIORAL

Eligibility Criteria

Age2 Years - 17 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Participants that qualify for the study will have one of the following health conditions:
  • Persistent asthma as defined by NHLBI guidelines
  • Chronic respiratory symptoms,
  • And/or have lead levels equal to or above 15 micrograms per deciliter.
  • They must be between the ages of 2 and 17 years of age
  • Stay in the home a minimum of 4 nights per week
  • They should reside in the KCEEC (Defined as the city limits of Kansas City Kansas or Kansas City Missouri).
  • They will also have lived in the same housing, either rental or self-owned, for at least 6 months and have a reasonable expectation of remaining in this housing for at least one additional year.
  • To qualify for the intervention phase of the study done by HHN,
  • The home must have no more than $2000 estimated intervention costs. Examples of houses that would not qualify include: A house that needs a new roof, a house with extensive amounts of flaking lead paint, a house with significant structural problems.

You may not qualify if:

  • Any children who do not meet the age and residency requirements.
  • Any home with more than $2000 worth of maintenance and repair problems. - Any home with emergent, life threatening conditions.
  • Children with other chronic diseases (leukemia, diabetes etc) will be referred through the HHN and CMH to appropriate medical services, agencies, organizations and other community resources.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Children's Mercy Hospital

Kansas City, Missouri, 64108, United States

Location

Related Publications (1)

  • Portnoy JM, Kwak K, Dowling P, VanOsdol T, Barnes C. Health effects of indoor fungi. Ann Allergy Asthma Immunol. 2005 Mar;94(3):313-9; quiz 319-22, 390. doi: 10.1016/S1081-1206(10)60982-9.

    PMID: 15801241BACKGROUND

MeSH Terms

Conditions

AsthmaRhinitisHypersensitivity

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateImmune System DiseasesRespiratory Tract InfectionsInfectionsNose DiseasesOtorhinolaryngologic Diseases

Study Officials

  • Charles S Barnes, Ph.D.

    Children's Mercy Hospital Kansas City

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 2, 2005

First Posted

September 5, 2005

Study Start

March 1, 2003

Study Completion

May 1, 2005

Last Updated

January 20, 2021

Record last verified: 2021-01

Locations

US(1)