NCT00140972

Brief Summary

A Study to Assess Etoricoxib versus Diclofenac in Chinese Patients with Osteoarthritis of the Knee or Hip

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
160

participants targeted

Target at P50-P75 for phase_4

Timeline
Completed

Started Dec 2004

Shorter than P25 for phase_4

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 3, 2004

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 27, 2005

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 27, 2005

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

August 30, 2005

Completed
2 days until next milestone

First Posted

Study publicly available on registry

September 1, 2005

Completed
Last Updated

August 15, 2024

Status Verified

February 1, 2022

Enrollment Period

7 months

First QC Date

August 30, 2005

Last Update Submit

August 12, 2024

Conditions

Osteoarthritis

Keywords

Arcoxia

Outcome Measures

Primary Outcomes (1)

  • WOMAC pain subscale

Secondary Outcomes (1)

  • WOMAC Physical function subscale; WOMAC Stiffness subscale; Patient Global Assessment of Response to Therapy; Investigator Global Assessment of Disease Status

Interventions

MK0663; etoricoxib / Duration of Treatment:4 WeeksDRUG
Comparator: diclofenac sodium tablet 75 mg / Duration of Treatment:4 WeeksDRUG

Eligibility Criteria

Age40 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Chinese males or females at least 40 years of age with osteoarthritis of the knee or hip

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Zhang F, Li Z, Yang N, Wu D, Sun L, Wu H. The clinical study of etoricoxib in the treatment of Chinese patients with osteoarthritis: a randomized double-blind trial. Chinese J of Rheum. 2013;17(5):307-312.

    RESULT

MeSH Terms

Conditions

Osteoarthritis

Interventions

Etoricoxib

Condition Hierarchy (Ancestors)

ArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic Diseases

Intervention Hierarchy (Ancestors)

SulfonesSulfur CompoundsOrganic ChemicalsPyridinesHeterocyclic Compounds, 1-RingHeterocyclic Compounds

Study Officials

  • Medical Monitor

    Merck Sharp & Dohme LLC

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 30, 2005

First Posted

September 1, 2005

Study Start

December 3, 2004

Primary Completion

June 27, 2005

Study Completion

June 27, 2005

Last Updated

August 15, 2024

Record last verified: 2022-02