NCT00136942

Brief Summary

The proportion of patients achieving LDL-C target as defined by Swiss cholesterol recommendations (AGLA-recommendations) across starting doses of 10 mg, 20 mg, 40 mg, and 80 mg of atorvastatin.

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
370

participants targeted

Target at P50-P75 for phase_3

Geographic Reach
1 country

20 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2005

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

August 25, 2005

Completed
4 days until next milestone

First Posted

Study publicly available on registry

August 29, 2005

Completed
Last Updated

February 18, 2021

Status Verified

February 1, 2021

First QC Date

August 25, 2005

Last Update Submit

February 17, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • The proportion of patients achieving LDL-C target as defined by local swiss AGLArecommendations across starting doses of 10 mg, 20 mg, 40 mg, and 80 mg of atorvastatin.

Secondary Outcomes (1)

  • The proportion of patients across different AGLA-categories (primary and secondary prevention) achieving LDL-C target as defined by AGLA-recommendations across starting doses of 10 mg, 20 mg, 40 mg, and 80 mg of atorvastatin.

Interventions

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Risk factors and diagnosis of dyslipidemia according to the AGLA-recommendations (see appendix B) at screening
  • LDL-C \< 6.0 mmol/l
  • Triglyceride level \< 5.0 mmol/l.

You may not qualify if:

  • Subjects receiving higher than "usual maintenance" doses of Lipid Lowering Therapy (LLT) at screening.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (20)

Pfizer Investigational Site

Binningen, Basel-Landschaft, Switzerland

Location

Pfizer Investigational Site

Liestal, Basel-Landschaft, Switzerland

Location

Pfizer Investigational Site

Basel, Canton of Basel-City, Switzerland

Location

Pfizer Investigational Site

Langenthal, Canton of Bern, Switzerland

Location

Pfizer Investigational Site

Thun, Canton of Bern, Switzerland

Location

Pfizer Investigational Site

Düdingen, Canton of Fribourg, Switzerland

Location

Pfizer Investigational Site

Geneva, Canton of Geneva, Switzerland

Location

Pfizer Investigational Site

Onex, Canton of Geneva, Switzerland

Location

Pfizer Investigational Site

Pfaeffikon, Canton of Schwyz, Switzerland

Location

Pfizer Investigational Site

Siebnen, Canton of Schwyz, Switzerland

Location

Pfizer Investigational Site

Écublens, Canton of Vaud, Switzerland

Location

Pfizer Investigational Site

Lausanne, Canton of Vaud, Switzerland

Location

Pfizer Investigational Site

Prilly, Canton of Vaud, Switzerland

Location

Pfizer Investigational Site

Unterägeri, Canton of Zug, Switzerland

Location

Pfizer Investigational Site

Zug, Canton of Zug, Switzerland

Location

Pfizer Investigational Site

Zurich, Canton of Zurich, Switzerland

Location

Pfizer Investigational Site

Lugano, Canton Ticino, Switzerland

Location

Pfizer Investigational Site

Malvaglia, Canton Ticino, Switzerland

Location

Pfizer Investigational Site

Melide, Canton Ticino, Switzerland

Location

Pfizer Investigational Site

Vezia, Canton Ticino, Switzerland

Location

Related Links

MeSH Terms

Conditions

Hyperlipidemias

Interventions

Atorvastatin

Condition Hierarchy (Ancestors)

DyslipidemiasLipid Metabolism DisordersMetabolic DiseasesNutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

PyrrolesAzolesHeterocyclic Compounds, 1-RingHeterocyclic CompoundsHeptanoic AcidsFatty AcidsLipids

Study Officials

  • Pfizer CT.gov Call Center

    Pfizer

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
phase 3
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 25, 2005

First Posted

August 29, 2005

Study Start

April 1, 2005

Last Updated

February 18, 2021

Record last verified: 2021-02

Locations