Influence of Binge Drinking on Glucose Metabolism in Patients With Type 1 Diabetes - A Pilot Study

NCT00135915 | Completed DMC

• 1 other identifier: BDEC ALC 1
• Study Type: observational
• Target: 10
• Locations: 1 country
• Sites: 1

Brief Summary

Although there is no evidence that individuals with type 1 diabetes have a different approach to alcohol compared to the background population, nevertheless, its use does have implications for patients mainly because of the risk of hypoglycaemia unawareness. However, binge drinking has been implicated as a factor in the development of ketoacidosis and is probably under-recognised. The aim of this study is to examine the effect of binge drinking on glucose, insulin, counter-regulatory hormones and other metabolites in patients with type 1 diabetes. It is hoped that data from this project will be used to develop a larger study comparing different treatment regimens for patients using alcohol to reduce the risks of hyperglycaemia as well as hypoglycaemia.

Conditions

Diabetes Mellitus, Type 1

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Males or females of at least 18 years of age who were diagnosed with Type 1 diabetes more than 5 years ago.

You may qualify if:

• Type 1 diabetes for \> 5 years
• Use of multiple daily injections of a basal insulin and a rapid acting component
• Regular consumption of modest amounts of alcohol

You may not qualify if:

• Type 2 diabetes
• Type I diabetes \< 5 years
• Excessive alcohol consumption
• Unstable diabetes

Sponsors & Collaborators

• The Royal Bournemouth Hospital: lead

Study Sites (1)

Royal Bournemouth Hospital

Bournemouth, Dorset, BH7 7DW, United Kingdom

Location

MeSH Terms

Conditions

Diabetes Mellitus, Type 1

Condition Hierarchy (Ancestors)

Diabetes Mellitus; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases; Autoimmune Diseases; Immune System Diseases

Study Officials

• David Kerr, Doctor

  The Royal Bournemouth Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CROSSOVER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: August 24, 2005
• First Posted: August 26, 2005
• Study Start: August 1, 2005
• Study Completion: February 1, 2007
• Last Updated: November 2, 2009

Record last verified: 2009-10

Locations

GB (1)