NCT00134277

Brief Summary

This study is a comparison of different medical devices for infragenual dilatation.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
35

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Sep 2004

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2004

Completed
12 months until next milestone

First Submitted

Initial submission to the registry

August 23, 2005

Completed
1 day until next milestone

First Posted

Study publicly available on registry

August 24, 2005

Completed
3.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2009

Completed
1.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2010

Completed
Last Updated

September 9, 2011

Status Verified

September 1, 2011

Enrollment Period

4.3 years

First QC Date

August 23, 2005

Last Update Submit

September 8, 2011

Conditions

Outcome Measures

Primary Outcomes (1)

  • Primary patency after 6 months

    After 6 months

Secondary Outcomes (1)

  • Proving the superiority or non-superiority of one treatment procedure to another treatment procedure

    After 6 months.

Study Arms (4)

Infragenual dilatation with stenting

ACTIVE COMPARATOR
Procedure: Infragenual dilatation with stenting

Infragenual dilatation with cutting balloon

ACTIVE COMPARATOR
Procedure: Infragenual dilatation with cutting balloon

Laser therapy

ACTIVE COMPARATOR
Procedure: Laser therapy

Infragenual dilatation

PLACEBO COMPARATOR
Procedure: Infragenual dilatation

Interventions

Infragenual dilatation

Infragenual dilatation

Infragenual dilatation with stenting

Infragenual dilatation with stenting

Infragenual dilatation with cutting balloon

Infragenual dilatation with cutting balloon
Laser therapyPROCEDURE

Laser therapy

Laser therapy

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Diabetes type I or II with diabetic angiopathy stage IIb to IV (Fontaine)
  • Atherosclerotic patients with distal angiopathy stage IIb to IV (Fontaine)

You may not qualify if:

  • Acute ischemia
  • Multisegmentaric damage above the knee
  • Sepsis: acute respiratory distress syndrome (ARDS), C-reactive protein (CRP) \> 30, white blood cell (WBC) \> 25,000
  • Acute myocardial infarction (AMI) during the last 14 days
  • Operative contraindication
  • Life expectancy \< 2 years
  • Blue toe syndrome (micro-embolisation)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital Ghent

Ghent, 9000, Belgium

Location

Related Links

MeSH Terms

Conditions

Diabetic AngiopathiesIntermittent Claudication

Interventions

StentsLaser Therapy

Condition Hierarchy (Ancestors)

Vascular DiseasesCardiovascular DiseasesDiabetes ComplicationsDiabetes MellitusEndocrine System DiseasesPeripheral Arterial DiseasePeripheral Vascular DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Prostheses and ImplantsEquipment and SuppliesTherapeuticsAblation TechniquesSurgical Procedures, Operative

Study Officials

  • Caren Randon, MD

    University Hospital, Ghent

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 23, 2005

First Posted

August 24, 2005

Study Start

September 1, 2004

Primary Completion

January 1, 2009

Study Completion

April 1, 2010

Last Updated

September 9, 2011

Record last verified: 2011-09

Locations