Psychodynamic Therapy for Treating Panic Disorder
Randomized Controlled Trial of Psychodynamic Psychotherapy vs. Applied Relaxation for Panic Disorder
2 other identifiers
interventional
49
1 country
1
Brief Summary
This study will determine the effectiveness of a manualized form of brief psychodynamic psychotherapy in comparison with applied relaxation training in treating adults with panic disorder.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for phase_2
Started Feb 2000
Longer than P75 for phase_2
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2000
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 1, 2005
CompletedStudy Completion
Last participant's last visit for all outcomes
July 1, 2005
CompletedFirst Submitted
Initial submission to the registry
August 5, 2005
CompletedFirst Posted
Study publicly available on registry
August 9, 2005
CompletedJune 27, 2013
June 1, 2013
4.9 years
August 5, 2005
June 26, 2013
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
PDSS (panic disorder severity scale)
termination, 2, 4, 6, 12 month f/u
Secondary Outcomes (3)
SDS (Sheehan disability scale)
termination, 2, 4, 6, 12 month f/u
HARS (Hamilton anxiety rating scale)
termination, 2, 4, 6, 12 month f/u
HDRS (Hamilton depression rating scale)
termination, 2, 4, 6, 12 month f/u
Study Arms (2)
1 PFPP
EXPERIMENTALPanic Focused Psychodynamic Psychotherapy
2 ART
ACTIVE COMPARATORApplied Relaxation Training
Interventions
Eligibility Criteria
You may qualify if:
- years old
- Primary DSM-IV panic disorder with or without agoraphobia
- Severity 5/8 minimum on the Anxiety Disorders Interview Schedule
You may not qualify if:
- Psychosis
- Unstable medication dosage
- Unwilling to discontinue ongoing psychotherapy
- Organic mental syndrome
- Substance use or abuse
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Weill Medical College
New York, New York, 10021, United States
Related Publications (3)
Gibbon S, Khalifa NR, Cheung NH, Vollm BA, McCarthy L. Psychological interventions for antisocial personality disorder. Cochrane Database Syst Rev. 2020 Sep 3;9(9):CD007668. doi: 10.1002/14651858.CD007668.pub3.
PMID: 32880104DERIVEDKlass ET, Milrod BL, Leon AC, Kay SJ, Schwalberg M, Li C, Markowitz JC. Does interpersonal loss preceding panic disorder onset moderate response to psychotherapy? An exploratory study. J Clin Psychiatry. 2009 Mar;70(3):406-11. doi: 10.4088/jcp.08m04248. Epub 2008 Nov 18.
PMID: 19026262DERIVEDMilrod BL, Leon AC, Barber JP, Markowitz JC, Graf E. Do comorbid personality disorders moderate panic-focused psychotherapy? An exploratory examination of the American Psychiatric Association practice guideline. J Clin Psychiatry. 2007 Jun;68(6):885-91. doi: 10.4088/jcp.v68n0610.
PMID: 17592913DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Barbara Milrod, M.D.
Weill Medical College
Study Design
- Study Type
- interventional
- Phase
- phase 2
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
August 5, 2005
First Posted
August 9, 2005
Study Start
February 1, 2000
Primary Completion
January 1, 2005
Study Completion
July 1, 2005
Last Updated
June 27, 2013
Record last verified: 2013-06