NCT00114075

Brief Summary

The purpose of this study is to evaluate the effects of pre-operative gait analysis testing on surgical outcomes in children with cerebral palsy who have problems walking.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
186

participants targeted

Target at P75+ for phase_2

Timeline
Completed

Started Jan 2005

Longer than P75 for phase_2

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2005

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

June 13, 2005

Completed
1 day until next milestone

First Posted

Study publicly available on registry

June 14, 2005

Completed
5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2010

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2010

Completed
Last Updated

July 18, 2012

Status Verified

August 1, 2011

Enrollment Period

5.5 years

First QC Date

June 13, 2005

Last Update Submit

July 17, 2012

Conditions

Keywords

gaitwalkingorthopedic surgeryorthopaedic surgery

Outcome Measures

Primary Outcomes (2)

  • Change in walking ability at 1 year

    1 year

  • Change in walking efficiency at 1 year

    1 year

Secondary Outcomes (3)

  • Change in gross motor function at 1 year

    1 year

  • Change in quality of life at 1 year

    1 year

  • Additional treatment needed at 1 year

    1 year

Study Arms (2)

Gait analysis

EXPERIMENTAL

Gait analysis report is available for treatment planning

Procedure: Surgery with gait analysis report

Control

ACTIVE COMPARATOR

Subject has gait analysis test, but report is not available for treatment planning

Procedure: Surgery without gait analysis report

Interventions

Orthopaedic surgery with access to gait analysis report

Gait analysis

Orthopaedic surgery without access to gait analysis report

Control

Eligibility Criteria

Age3 Years - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Diagnosis of cerebral palsy
  • Able to walk
  • Under evaluation for orthopedic surgery to correct walking problem(s)

You may not qualify if:

  • Orthopaedic surgery in past 1 year
  • Injection of botulinum toxin in past 6 months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Shriners Hospital for Children, Los Angeles

Los Angeles, California, 90020, United States

Location

Childrens Hospital Los Angeles

Los Angeles, California, 90027, United States

Location

Related Publications (1)

  • Kay RM, Dennis S, Rethlefsen S, Reynolds RA, Skaggs DL, Tolo VT. The effect of preoperative gait analysis on orthopaedic decision making. Clin Orthop Relat Res. 2000 Mar;(372):217-22. doi: 10.1097/00003086-200003000-00023.

    PMID: 10738430BACKGROUND

Related Links

MeSH Terms

Conditions

Cerebral Palsy

Interventions

Surgical Procedures, Operative

Condition Hierarchy (Ancestors)

Brain Damage, ChronicBrain DiseasesCentral Nervous System DiseasesNervous System Diseases

Study Officials

  • Tishya AL Wren, Ph.D.

    Children's Hospital Los Angeles

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
FED
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 13, 2005

First Posted

June 14, 2005

Study Start

January 1, 2005

Primary Completion

July 1, 2010

Study Completion

July 1, 2010

Last Updated

July 18, 2012

Record last verified: 2011-08

Locations