NCT00108537

Brief Summary

The primary objective of this study is to determine which is the better approach to smoking cessation in veterans: bupropion combined with transdermal nicotine or high dose nicotine replacement therapy (NRT) using transdermal nicotine combined with nicotine inhaler.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Oct 2003

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2003

Completed
1.5 years until next milestone

First Submitted

Initial submission to the registry

April 15, 2005

Completed
3 days until next milestone

First Posted

Study publicly available on registry

April 18, 2005

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2005

Completed
Last Updated

April 4, 2008

Status Verified

October 1, 2006

First QC Date

April 15, 2005

Last Update Submit

April 2, 2008

Conditions

Tobacco Use Disorder

Keywords

smokingnicotinedrug therapysmoking cessation

Interventions

bupropion and transdermal patchDRUG
transdermal patch and nicotine inhalerDRUG

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Readiness to set a quit date in the next two weeks,
  • Current smoking of at least 15 cigarettes a day

You may not qualify if:

  • Current untreated depression or receiving treatment for depression,
  • History of seizures, major head injury, or other predisposition for seizures

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Denver VA Medical Center

Denver, Colorado, 80220, United States

Location

MeSH Terms

Conditions

Tobacco Use DisorderSmokingSmoking Cessation

Interventions

BupropionTransdermal PatchNicotine

Condition Hierarchy (Ancestors)

Substance-Related DisordersChemically-Induced DisordersMental DisordersBehaviorHealth Behavior

Intervention Hierarchy (Ancestors)

PropiophenonesKetonesOrganic ChemicalsEquipment and SuppliesSolanaceous AlkaloidsAlkaloidsHeterocyclic CompoundsPyridinesHeterocyclic Compounds, 1-Ring

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Sponsor Type
FED

Study Record Dates

First Submitted

April 15, 2005

First Posted

April 18, 2005

Study Start

October 1, 2003

Study Completion

September 1, 2005

Last Updated

April 4, 2008

Record last verified: 2006-10

Locations

US(1)